Literature DB >> 15538225

Laparoscopic radical nephrectomy for large (greater than 7 cm, T2) renal tumors.

Andrew P Steinberg1, Antonio Finelli, Mihir M Desai, Sidney C Abreu, Anup P Ramani, Massimiliano Spaliviero, Lisa Rybicki, Jihad Kaouk, Andrew C Novick, Inderbir S Gill.   

Abstract

PURPOSE: Laparoscopic radical nephrectomy has emerged as a standard of care in appropriate candidates with clinical stage T1 renal tumors (7 cm or less). Herein we present our experience with laparoscopic radical nephrectomy for clinical stage T2 tumors (greater than 7 cm).
MATERIALS AND METHODS: Patients undergoing laparoscopic radical nephrectomy between September 1997 and July 2003 were retrospectively subdivided into group LAPT1-166 with tumor size 7 cm and group LAPT2-65 with tumor size greater than 7 cm. Also, group LAPT2 was compared with a group of 34 contemporary, comparable patients undergoing open radical nephrectomy for tumor greater than 7 cm (group OPENT2).
RESULTS: Compared with group LAPT1, group LAPT2 had younger patients, larger tumors and greater blood loss (100 vs 200 ml) (each p <0.001). Importantly operative time, analgesic requirements, hospital stay, and convalescence and complication rates were comparable. Group LAPT2 and group OPENT2 patients had similar sized tumors (9.2 and 9.9 cm, respectively) but shorter operative time (p = 0.03), lesser blood loss (p <0.001), shorter hospital stay (p <0.001) and more rapid convalescence (p = 0.02) occurred in LAPT2.
CONCLUSIONS: Laparoscopic radical nephrectomy for stage T2 renal masses (greater than 7 cm) is feasible and efficacious. Laparoscopic nephrectomy offers the advantages of decreased blood loss, shorter hospital stay and more rapid recovery over open radical nephrectomy for comparable tumors greater than 7 cm. Although surgical outcomes are comparable with laparoscopic radical nephrectomy for smaller tumors (7 cm or less), adequate laparoscopic experience is necessary before performing radical nephrectomy for large T2 tumors.

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Year:  2004        PMID: 15538225     DOI: 10.1097/01.ju.0000140961.53335.04

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  29 in total

1.  Management of kidney cancer: canadian kidney cancer forum consensus update 2011.

Authors:  Mas Jewett; A Finelli; C Kollmannsberger; L Wood; L Legere; J Basiuk; C Canil; D Heng; N Reaume; S Tanguay; M Atkins; G Bjarnason; J Dancey; M Evans; N Fleshner; M Haider; A Kapoor; R Uzzo; D Maskens; D Soulieres; G Yousef; N Basappa; N Bendali; P Black; N Blais; I Cagiannos; M Care; R Chow; H Chung; P Czaykowski; D Derosa; K Durrant; S Ellard; G Farquharson; C Filion-Brulotte; J Gingerich; L Godbout; R Grant; W Hamilton; W Kassouf; G Kurban; K Lane; Jb Lattouf; D Lau; M Leveridge; J McCarthy; R Moore; S North; P O'brien; E Pituskin; P Racine; R Rendon; A So; S Sridhar; K Stubbs; Z Su; L Taylor; T Udall; P Venner; W Vogel; S Yap; P Yau; M Cooper; N Giroux; D Miron; D Mosher; K Ross; J Willacy
Journal:  Can Urol Assoc J       Date:  2012-02       Impact factor: 1.862

2.  Evaluating the perioperative safety of laparoscopic radical nephrectomy for large, non-metastatic renal tumours: a comparative analysis of T1-T2 with T3a tumours.

Authors:  E M Bolton; D Hennessy; P E Lonergan; F T Darcy; R P Manecksha; T H Lynch
Journal:  Ir J Med Sci       Date:  2017-07-13       Impact factor: 1.568

3.  A novel approach to locate renal artery during retroperitoneal laparoendoscopic single-site radical nephrectomy.

Authors:  Lixin Shi; Wei Cai; Juan Dong; Jiangping Gao; Hongzhao Li; Shengkun Sun; Qiang Zu; Xu Zhang
Journal:  Int J Clin Exp Med       Date:  2014-07-15

4.  Surgical management of renal cell carcinoma: Canadian Kidney Cancer Forum Consensus.

Authors:  Ricardo A Rendon; Anil Kapoor; Rodney Breau; Michael Leveridge; Andrew Feifer; Peter C Black; Alan So
Journal:  Can Urol Assoc J       Date:  2014-05       Impact factor: 1.862

5.  Obesity is an adverse factor on laparoscopic radical nephrectomy for t2 but not t1 renal cell carcinoma.

Authors:  Se Yun Kwon; Jae Jun Bae; Jung Gon Lee; Seock Hwan Choi; Bum Soo Kim; Eun Sang Yoo; Tae Gyun Kwon; Tae-Hwan Kim
Journal:  Korean J Urol       Date:  2011-08-22

6.  A prospective comparison of laparoscopic and robotic radical nephrectomy for T1-2N0M0 renal cell carcinoma.

Authors:  Ashok K Hemal; Anup Kumar
Journal:  World J Urol       Date:  2008-08-13       Impact factor: 4.226

7.  Management of kidney cancer: Canadian Kidney Cancer Forum Consensus Statement.

Authors: 
Journal:  Can Urol Assoc J       Date:  2008-06       Impact factor: 1.862

8.  Evaluation of laparoscopic radical cystectomy for loco-regionally advanced bladder cancer.

Authors:  Ashok K Hemal; Surendra B Kolla; Pankaj Wadhwa
Journal:  World J Urol       Date:  2007-11-21       Impact factor: 4.226

9.  Oncologic outcome of 132 cases of laparoscopic radical nephrectomy with intact specimen removal for T1-2N0M0 renal cell carcinoma.

Authors:  Ashok K Hemal; Anup Kumar; Narmada P Gupta; Rajeev Kumar
Journal:  World J Urol       Date:  2007-09-05       Impact factor: 4.226

Review 10.  Long-term outcomes of the surgical management of renal cell carcinoma.

Authors:  John S Lam; Arie S Belldegrun; Allan J Pantuck
Journal:  World J Urol       Date:  2006-02-15       Impact factor: 4.226

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