Literature DB >> 15509763

Human embryonic stem cells: prospects for development.

Martin F Pera1, Alan O Trounson.   

Abstract

It is widely anticipated that human embryonic stem (ES) cells will serve as an experimental model for studying early development in our species, and, conversely, that studies of development in model systems, the mouse in particular, will inform our efforts to manipulate human stem cells in vitro. A comparison of primate and mouse ES cells suggests that a common underlying blueprint for the pluripotent state has undergone significant species-specific modification. As we discuss here, technical advances in the propagation and manipulation of human ES cells have improved our understanding of their growth and differentiation, providing the potential to investigate early human development and to develop new clinical therapies.

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Year:  2004        PMID： 15509763     DOI： 10.1242/dev.01451

Source DB:  PubMed          Journal:  Development        ISSN： 0950-1991            Impact factor:   6.868


  66 in total

Review 1.  Vascular potential of human pluripotent stem cells.

Authors:  Ionela Iacobas; Archana Vats; Karen K Hirschi
Journal:  Arterioscler Thromb Vasc Biol       Date:  2010-05-07       Impact factor: 8.311

Review 2.  Extrinsic regulation of pluripotent stem cells.

Authors:  Martin F Pera; Patrick P L Tam
Journal:  Nature       Date:  2010-06-10       Impact factor: 49.962

3.  WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate.

Authors:  Alan W Leung; Barbara Murdoch; Ahmed F Salem; Maneeshi S Prasad; Gustavo A Gomez; Martín I García-Castro
Journal:  Development       Date:  2016-02-01       Impact factor: 6.868

4.  Core transcriptional regulatory circuitry in human embryonic stem cells.

Authors:  Laurie A Boyer; Tong Ihn Lee; Megan F Cole; Sarah E Johnstone; Stuart S Levine; Jacob P Zucker; Matthew G Guenther; Roshan M Kumar; Heather L Murray; Richard G Jenner; David K Gifford; Douglas A Melton; Rudolf Jaenisch; Richard A Young
Journal:  Cell       Date:  2005-09-23       Impact factor: 41.582

5.  Youthful prospects for human stem-cell therapy. In another few decades, revised attitudes toward stem cells could lead to disease prevention and life extension.

Authors:  Nadia Rosenthal
Journal:  EMBO Rep       Date:  2005-07       Impact factor: 8.807

6.  Control of developmental regulators by Polycomb in human embryonic stem cells.

Authors:  Tong Ihn Lee; Richard G Jenner; Laurie A Boyer; Matthew G Guenther; Stuart S Levine; Roshan M Kumar; Brett Chevalier; Sarah E Johnstone; Megan F Cole; Kyo-ichi Isono; Haruhiko Koseki; Takuya Fuchikami; Kuniya Abe; Heather L Murray; Jacob P Zucker; Bingbing Yuan; George W Bell; Elizabeth Herbolsheimer; Nancy M Hannett; Kaiming Sun; Duncan T Odom; Arie P Otte; Thomas L Volkert; David P Bartel; Douglas A Melton; David K Gifford; Rudolf Jaenisch; Richard A Young
Journal:  Cell       Date:  2006-04-21       Impact factor: 41.582

Review 7.  Development and differentiation of neural rosettes derived from human embryonic stem cells.

Authors:  Patricia G Wilson; Steve S Stice
Journal:  Stem Cell Rev       Date:  2006       Impact factor: 5.739

8.  Immortalized keratinocyte lines derived from human embryonic stem cells.

Authors:  Shiro Iuchi; Sally Dabelsteen; Karen Easley; James G Rheinwald; Howard Green
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-30       Impact factor: 11.205

9.  A chromatin landmark and transcription initiation at most promoters in human cells.

Authors:  Matthew G Guenther; Stuart S Levine; Laurie A Boyer; Rudolf Jaenisch; Richard A Young
Journal:  Cell       Date:  2007-07-13       Impact factor: 41.582

Review 10.  [Stem cells--cloning, plasticity, bioethic].

Authors:  Pamina Pflegerl; Thomas Keller; Brigitte Hantusch; Thomas Sören Hoffmann; Lukas Kenner
Journal:  Wien Med Wochenschr       Date:  2008
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