OBJECTIVE: Stereotactic radiosurgery requires the highest degree of accuracy in target identification and localization. When targeting paraspinal lesions, the CyberKnife radiosurgical system (Accuray, Inc., Sunnyvale, CA) uses implanted stainless steel fiducials. The purpose of this study was to evaluate the total system for clinically relevant accuracy of this approach. METHODS: The clinically relevant accuracy of the CyberKnife depends on 1) the accuracy of beam delivery, which in turn represents a compilation of robot and camera image-tracking errors, and 2) the inherent accuracy of target localization that stems from computed tomographic imaging and treatment planning. The clinically relevant accuracy was measured at three different CyberKnife facilities using head and torso phantoms loaded with packs of radiochromic film and expressed as a displacement of the dose contours from the treatment planning. RESULTS: The mean clinically relevant error, as measured at three different CyberKnife facilities, was determined to be 0.7 +/- 0.3 mm, which did not vary with computed tomographic slice thickness in a range of 0.625 to 1.5 mm. The average treatment delivery precision was 0.3 +/- 0.1 mm. Fiducial tracking error was less than 0.3 mm for radial translations up to 14 mm and less than 0.7 mm for rotations up to 4.5 degrees. CONCLUSION: For the treatment of relatively stationary spinal lesions targeted with fiducial tracking, the CyberKnife system is capable of submillimeter accuracy.
OBJECTIVE: Stereotactic radiosurgery requires the highest degree of accuracy in target identification and localization. When targeting paraspinal lesions, the CyberKnife radiosurgical system (Accuray, Inc., Sunnyvale, CA) uses implanted stainless steel fiducials. The purpose of this study was to evaluate the total system for clinically relevant accuracy of this approach. METHODS: The clinically relevant accuracy of the CyberKnife depends on 1) the accuracy of beam delivery, which in turn represents a compilation of robot and camera image-tracking errors, and 2) the inherent accuracy of target localization that stems from computed tomographic imaging and treatment planning. The clinically relevant accuracy was measured at three different CyberKnife facilities using head and torso phantoms loaded with packs of radiochromic film and expressed as a displacement of the dose contours from the treatment planning. RESULTS: The mean clinically relevant error, as measured at three different CyberKnife facilities, was determined to be 0.7 +/- 0.3 mm, which did not vary with computed tomographic slice thickness in a range of 0.625 to 1.5 mm. The average treatment delivery precision was 0.3 +/- 0.1 mm. Fiducial tracking error was less than 0.3 mm for radial translations up to 14 mm and less than 0.7 mm for rotations up to 4.5 degrees. CONCLUSION: For the treatment of relatively stationary spinal lesions targeted with fiducial tracking, the CyberKnife system is capable of submillimeter accuracy.
Authors: Kush Goyal; Douglas Einstein; Rafael A Ibarra; Min Yao; Charles Kunos; Rod Ellis; James Brindle; Deepjot Singh; Jeffrey Hardacre; Yuxia Zhang; Jeffrey Fabians; Gary Funkhouser; Mitchell Machtay; Juan R Sanabria Journal: J Surg Res Date: 2011-09-05 Impact factor: 2.192
Authors: Ning Wen; Joshua Kim; Anthony Doemer; Carri Glide-Hurst; Indrin J Chetty; Chang Liu; Eric Laugeman; Ilma Xhaferllari; Akila Kumarasiri; James Victoria; Maria Bellon; Steve Kalkanis; M Salim Siddiqui; Benjamin Movsas Journal: Radiother Oncol Date: 2018-05-25 Impact factor: 6.280
Authors: Eric Oermann; Brian T Collins; Kelly T Erickson; Xia Yu; Sue Lei; Simeng Suy; Heather N Hanscom; Joy Kim; Hyeon U Park; Andrew Eldabh; Christopher Kalhorn; Kevin McGrail; Deepa Subramaniam; Walter C Jean; Sean P Collins Journal: J Hematol Oncol Date: 2010-06-09 Impact factor: 17.388