| Literature DB >> 15504891 |
Harald Noedl1, Paktiya Teja-Isavadharm, Robert Scott Miller.
Abstract
A simple, nonisotopic, semiautomated bioassay for the measurement of antimalarial drug levels in plasma or serum based on the quantitation of histidine-rich protein II in malaria culture is presented. The assay requires only small sample volumes and was found to be highly sensitive and reproducible. The results closely paralleled those obtained with isotopic bioassays (R = 0.988, P < 0.001) and high-performance liquid chromatography-electrochemical detection (R = 0.978, P < 0.001).Entities:
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Year: 2004 PMID: 15504891 PMCID: PMC525391 DOI: 10.1128/AAC.48.11.4485-4487.2004
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191