| Literature DB >> 15504883 |
Xinying Li1, Noriel Mariano, James J Rahal, Carl M Urban, Karl Drlica.
Abstract
Stepwise selection of ciprofloxacin-resistant Haemophilus influenzae mutants produced first-, second-, third-, and fourth-step substitutions in GyrA (S84Y), ParC (S84R), GyrA (D88N), and ParC (E88K), respectively. Successive mutations raised the mutant selection window. The wild-type selection window for garenoxacin, levofloxacin, and moxifloxacin was also measured.Entities:
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Year: 2004 PMID: 15504883 PMCID: PMC525419 DOI: 10.1128/AAC.48.11.4460-4462.2004
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191