Literature DB >> 15486464

The Farnesoid X Receptor (FXR) as modulator of bile acid metabolism.

Folkert Kuipers1, Thierry Claudel, Ekkehard Sturm, Bart Staels.   

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Year:  2004        PMID： 15486464     DOI： 10.1023/B:REMD.0000045103.00467.9a

Source DB:  PubMed          Journal:  Rev Endocr Metab Disord        ISSN： 1389-9155            Impact factor:   6.514


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  69 in total

1.  Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway.

Authors:  S Gupta; R T Stravitz; P Dent; P B Hylemon
Journal:  J Biol Chem       Date:  2001-02-13       Impact factor: 5.157

2.  The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp.

Authors:  L A Denson; E Sturm; W Echevarria; T L Zimmerman; M Makishima; D J Mangelsdorf; S J Karpen
Journal:  Gastroenterology       Date:  2001-07       Impact factor: 22.682

3.  Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.

Authors:  P L Jansen; S S Strautnieks; E Jacquemin; M Hadchouel; E M Sokal; G J Hooiveld; J H Koning; A De Jager-Krikken; F Kuipers; F Stellaard; C M Bijleveld; A Gouw; H Van Goor; R J Thompson; M Müller
Journal:  Gastroenterology       Date:  1999-12       Impact factor: 22.682

4.  Identification of a nuclear receptor for bile acids.

Authors:  M Makishima; A Y Okamoto; J J Repa; H Tu; R M Learned; A Luk; M V Hull; K D Lustig; D J Mangelsdorf; B Shan
Journal:  Science       Date:  1999-05-21       Impact factor: 47.728

Review 5.  Nuclear receptor regulation of cholesterol and bile acid metabolism.

Authors:  J J Repa; D J Mangelsdorf
Journal:  Curr Opin Biotechnol       Date:  1999-12       Impact factor: 9.740

6.  Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer.

Authors:  J Grober; I Zaghini; H Fujii; S A Jones; S A Kliewer; T M Willson; T Ono; P Besnard
Journal:  J Biol Chem       Date:  1999-10-15       Impact factor: 5.157

7.  Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver.

Authors:  C J Soroka; J M Lee; F Azzaroli; J L Boyer
Journal:  Hepatology       Date:  2001-04       Impact factor: 17.425

8.  Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.

Authors:  Maria Rius; Anne T Nies; Johanna Hummel-Eisenbeiss; Gabriele Jedlitschky; Dietrich Keppler
Journal:  Hepatology       Date:  2003-08       Impact factor: 17.425

9.  Farnesoid X receptor regulates bile acid-amino acid conjugation.

Authors:  Parinaz C Pircher; Jennifer L Kitto; Mary L Petrowski; Rajendra K Tangirala; Eric D Bischoff; Ira G Schulman; Stefan K Westin
Journal:  J Biol Chem       Date:  2003-05-16       Impact factor: 5.157

10.  Identification of a nuclear receptor that is activated by farnesol metabolites.

Authors:  B M Forman; E Goode; J Chen; A E Oro; D J Bradley; T Perlmann; D J Noonan; L T Burka; T McMorris; W W Lamph; R M Evans; C Weinberger
Journal:  Cell       Date:  1995-06-02       Impact factor: 41.582
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  12 in total

1.  A novel heterozygous NR1H4 termination codon mutation in idiopathic infantile cholestasis.

Authors:  Xiu-Qi Chen; Lin-Lin Wang; Qing-Wen Shan; Qing Tang; Ya-Nan Deng; Shu-Jun Lian; Xiang Yun
Journal:  World J Pediatr       Date:  2011-06-01       Impact factor: 2.764

2.  Transactivation of the hepatitis B virus core promoter by the nuclear receptor FXRalpha.

Authors:  Christophe Ramière; Caroline Scholtès; Olivier Diaz; Vinca Icard; Laure Perrin-Cocon; Mary-Anne Trabaud; Vincent Lotteau; Patrice André
Journal:  J Virol       Date:  2008-09-03       Impact factor: 5.103

Review 3.  Mechanisms of disease: Inborn errors of bile acid synthesis.

Authors:  Shikha S Sundaram; Kevin E Bove; Mark A Lovell; Ronald J Sokol
Journal:  Nat Clin Pract Gastroenterol Hepatol       Date:  2008-06-24

4.  An increased flux through the glucose 6-phosphate pool in enterocytes delays glucose absorption in Fxr-/- mice.

Authors:  Theo H van Dijk; Aldo Grefhorst; Maaike H Oosterveer; Vincent W Bloks; Bart Staels; Dirk-Jan Reijngoud; Folkert Kuipers
Journal:  J Biol Chem       Date:  2009-02-09       Impact factor: 5.157

Review 5.  Nutritional lipidomics: molecular metabolism, analytics, and diagnostics.

Authors:  Jennifer T Smilowitz; Angela M Zivkovic; Yu-Jui Yvonne Wan; Steve M Watkins; Malin L Nording; Bruce D Hammock; J Bruce German
Journal:  Mol Nutr Food Res       Date:  2013-07-01       Impact factor: 5.914

6.  AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids.

Authors:  Daniel R Schmidt; Samuel Schmidt; Sam R Holmstrom; Makoto Makishima; Ruth T Yu; Carolyn L Cummins; David J Mangelsdorf; Steven A Kliewer
Journal:  J Biol Chem       Date:  2010-11-16       Impact factor: 5.157

7.  Effects of bile acids and the bile acid receptor FXR agonist on the respiratory rhythm in the in vitro brainstem medulla slice of neonatal Sprague-Dawley rats.

Authors:  Cong Zhao; Xianbao Wang; Yuling Cong; Yi Deng; Yijun Xu; Aihua Chen; Yanru Yin
Journal:  PLoS One       Date:  2014-11-18       Impact factor: 3.240

Review 8.  Current therapies in alleviating liver disorders and cancers with a special focus on the potential of vitamin D.

Authors:  Shahida Khan; Ashraf Ali; Sarah Khan; Ahmed Bakillah; Ghazi Damanhouri; Aziz Khan; Ahmad Makki; Ibtehal AlAnsari; Naheed Banu
Journal:  Nutr Metab (Lond)       Date:  2018-02-09       Impact factor: 4.169

Review 9.  Bile acid nuclear receptor FXR and digestive system diseases.

Authors:  Lili Ding; Li Yang; Zhengtao Wang; Wendong Huang
Journal:  Acta Pharm Sin B       Date:  2015-02-25       Impact factor: 11.413

10.  Morphologic Damage of Rat Alveolar Epithelial Type II Cells Induced by Bile Acids Could Be Ameliorated by Farnesoid X Receptor Inhibitor Z-Guggulsterone In Vitro.

Authors:  Jieqin Wang; Yaowei Huang; Xusheng Hou; Wenyu Wu; Lei Nie; Yinghong Tian; Yanmeng Lu; Yanru Yin
Journal:  Biomed Res Int       Date:  2016-06-01       Impact factor: 3.411
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