Literature DB >> 15455260

Pasteurella multocida toxin as a tool for studying Gq signal transduction.

B A Wilson1, M Ho.   

Abstract

Pasteurella multocida toxin (PMT) stimulates and subsequently uncouples phospholipase C (PLC) signal transduction through its selective action on the Galphaq subunit. This review summarizes what is currently known about the molecular action of PMT on Gq and the resulting cellular effects. Examples are presented illustrating the use of PMT as a powerful tool for dissecting the molecular mechanisms involving pertussis toxin (PT)-insensitive heterotrimeric G proteins.

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Year:  2004        PMID： 15455260      PMCID： PMC1761692          DOI： 10.1007/s10254-004-0032-6

Source DB:  PubMed          Journal:  Rev Physiol Biochem Pharmacol        ISSN： 0303-4240            Impact factor:   5.545


  92 in total

1.  Association of Pasteurella multocida toxin with vimentin.

Authors:  Hiroaki Shime; Takahiro Ohnishi; Kaori Nagao; Kiyomasa Oka; Toshifumi Takao; Yasuhiko Horiguchi
Journal:  Infect Immun       Date:  2002-11       Impact factor: 3.441

2.  Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly.

Authors:  Parmesh Dutt; Lars Kjoller; Maryann Giel; Alan Hall; Deniz Toksoz
Journal:  FEBS Lett       Date:  2002-11-20       Impact factor: 4.124

3.  Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.

Authors:  Stephan Vogt; Robert Grosse; Günter Schultz; Stefan Offermanns
Journal:  J Biol Chem       Date:  2003-05-27       Impact factor: 5.157

Review 4.  Gating of GIRK channels: details of an intricate, membrane-delimited signaling complex.

Authors:  Rona Sadja; Noga Alagem; Eitan Reuveny
Journal:  Neuron       Date:  2003-07-03       Impact factor: 17.173

5.  Stimulation of the alpha1A adrenergic receptor inhibits PDGF-induced PDGF beta receptor Tyr751 phosphorylation and PI 3-kinase activation.

Authors:  Hong-Ying Lin; Lisa M Ballou; Richard Z Lin
Journal:  FEBS Lett       Date:  2003-04-10       Impact factor: 4.124

6.  Modulation of the humoral immune response of swine and mice mediated by toxigenic Pasteurella multocida.

Authors:  Robert W Jordan; Timothy D C Hamilton; Christine M Hayes; Dilip Patel; Philip H Jones; John M Roe; Neil A Williams
Journal:  FEMS Immunol Med Microbiol       Date:  2003-10-24

Review 7.  The journey of tetanus and botulinum neurotoxins in neurons.

Authors:  Giovanna Lalli; Stephanie Bohnert; Katrin Deinhardt; Carole Verastegui; Giampietro Schiavo
Journal:  Trends Microbiol       Date:  2003-09       Impact factor: 17.079

Review 8.  Galpha12 and Galpha13 as key regulatory mediator in signal transduction.

Authors:  Hitoshi Kurose
Journal:  Life Sci       Date:  2003-12-05       Impact factor: 5.037

9.  Calcium signaling through phospholipase C activates dendritic cells to mature and is necessary for the activation and maturation of dendritic cells induced by diverse agonists.

Authors:  Kenneth C Bagley; Sayed F Abdelwahab; Robert G Tuskan; George K Lewis
Journal:  Clin Diagn Lab Immunol       Date:  2004-01

10.  Pasteurella multocida toxin facilitates inositol phosphate formation by bombesin through tyrosine phosphorylation of G alpha q.

Authors:  Michael R Baldwin; Gillian D Pullinger; Alistair J Lax
Journal:  J Biol Chem       Date:  2003-06-10       Impact factor: 5.157
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  10 in total

Review 1.  Probing heterotrimeric G protein activation: applications to biased ligands.

Authors:  Colette Denis; Aude Saulière; Segolene Galandrin; Jean-Michel Sénard; Céline Galés
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

2.  Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.

Authors:  Akiyuki Nishimura; Ken Kitano; Jun Takasaki; Masatoshi Taniguchi; Norikazu Mizuno; Kenji Tago; Toshio Hakoshima; Hiroshi Itoh
Journal:  Proc Natl Acad Sci U S A       Date:  2010-07-16       Impact factor: 11.205

3.  Membrane interaction of Pasteurella multocida toxin involves sphingomyelin.

Authors:  Michael C Brothers; Mengfei Ho; Ram Maharjan; Nathan C Clemons; Yuka Bannai; Mark A Waites; Melinda J Faulkner; Theresa B Kuhlenschmidt; Mark S Kuhlenschmidt; Steven R Blanke; Chad M Rienstra; Brenda A Wilson
Journal:  FEBS J       Date:  2011-10-20       Impact factor: 5.542

Review 4.  Recent insights into Pasteurella multocida toxin and other G-protein-modulating bacterial toxins.

Authors:  Brenda A Wilson; Mengfei Ho
Journal:  Future Microbiol       Date:  2010-08       Impact factor: 3.165

Review 5.  Cargo-delivery platforms for targeted delivery of inhibitor cargos against botulism.

Authors:  Brenda A Wilson; Mengfei Ho
Journal:  Curr Top Med Chem       Date:  2014       Impact factor: 3.295

6.  Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells.

Authors:  Dennis J Grab; Jose C Garcia-Garcia; Olga V Nikolskaia; Yuri V Kim; Amanda Brown; Carlos A Pardo; Yongqing Zhang; Kevin G Becker; Brenda A Wilson; Ana Paula C de A Lima; Julio Scharfstein; J Stephen Dumler
Journal:  PLoS Negl Trop Dis       Date:  2009-07-21

7.  The C3 domain of Pasteurella multocida toxin is the minimal domain responsible for activation of Gq-dependent calcium and mitogenic signaling.

Authors:  Leila R Aminova; Shuhong Luo; Yuka Bannai; Mengfei Ho; Brenda A Wilson
Journal:  Protein Sci       Date:  2008-03-27       Impact factor: 6.725

8.  Application of intact cell-based NFAT-beta-lactamase reporter assay for Pasteurella multocida toxin-mediated activation of calcium signaling pathway.

Authors:  Shuhong Luo; Mengfei Ho; Brenda A Wilson
Journal:  Toxicon       Date:  2007-11-23       Impact factor: 3.033

9.  Arf6-dependent intracellular trafficking of Pasteurella multocida toxin and pH-dependent translocation from late endosomes.

Authors:  Tana L Repella; Mengfei Ho; Tracy P M Chong; Yuka Bannai; Brenda A Wilson
Journal:  Toxins (Basel)       Date:  2011-03-16       Impact factor: 4.546

Review 10.  Gq-Coupled Receptors in Autoimmunity.

Authors:  Lu Zhang; Guixiu Shi
Journal:  J Immunol Res       Date:  2016-01-17       Impact factor: 4.818
  10 in total

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