| Literature DB >> 12379728 |
Hiroaki Shime1, Takahiro Ohnishi, Kaori Nagao, Kiyomasa Oka, Toshifumi Takao, Yasuhiko Horiguchi.
Abstract
To help understand the molecular mechanisms of Pasteurella multocida toxin (PMT) action, we searched for a cellular protein interacting with PMT. The ligand overlay assay revealed a 60-kDa cellular protein that binds to a region from the 840th to 985th amino acids of the toxin. This protein was identified as vimentin by peptide mass fingerprinting. The N-terminal head domain of vimentin was further found to be responsible for the binding to the toxin.Mesh:
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Year: 2002 PMID: 12379728 PMCID: PMC130396 DOI: 10.1128/IAI.70.11.6460-6463.2002
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441