Literature DB >> 15388467

Correlation between in vitro susceptibility of Scedosporium apiospermum to voriconazole and in vivo outcome of scedosporiosis in guinea pigs.

Javier Capilla1, Josep Guarro.   

Abstract

We have evaluated the efficacy of voriconazole (VRC) in a systemic infection by Scedosporium apiospermum in immunodepressed guinea pigs. Animals were infected with two strains; one required a VRC MIC of 0.5 to 1 microg/ml, common for this fungus, and the other required a high MIC (8 microg/ml), unusual in this species. VRC prolonged survival and reduced fungal load in kidney and brain tissues of the animals infected with the first strain but was unable to prolong survival or to reduce fungal load in brain tissue for the latter strain.

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Year:  2004        PMID： 15388467      PMCID： PMC521912          DOI： 10.1128/AAC.48.10.4009-4011.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  20 in total

1.  Invasive pulmonary infection due to Scedosporium apiospermum in two children with chronic granulomatous disease.

Authors:  N Jabado; J L Casanova; E Haddad; F Dulieu; J C Fournet; B Dupont; A Fischer; C Hennequin; S Blanche
Journal:  Clin Infect Dis       Date:  1998-12       Impact factor: 9.079

2.  Use of voriconazole in treatment of Scedosporium apiospermum infection: case report.

Authors:  C Girmenia; G Luzi; M Monaco; P Martino
Journal:  J Clin Microbiol       Date:  1998-05       Impact factor: 5.948

3.  Comparative in-vitro activity of voriconazole (UK-109,496) and six other antifungal agents against clinical isolates of Scedosporium prolificans and Scedosporium apiospermum.

Authors:  M Cuenca-Estrella; B Ruiz-Díez; J V Martínez-Suárez; A Monzón; J L Rodríguez-Tudela
Journal:  J Antimicrob Chemother       Date:  1999-01       Impact factor: 5.790

4.  Efficacy of voriconazole against invasive pulmonary aspergillosis in a guinea-pig model.

Authors:  P H Chandrasekar; J Cutright; E Manavathu
Journal:  J Antimicrob Chemother       Date:  2000-05       Impact factor: 5.790

5.  Meningitis caused by Pseudallescheria boydii treated with voriconazole.

Authors:  G Poza; J Montoya; C Redondo; J Ruiz; N Vila; J L Rodriguez-Tudela; A Cerón; E Simarro
Journal:  Clin Infect Dis       Date:  2000-06       Impact factor: 9.079

Review 6.  Pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage: case report and literature review of central nervous system pseudallescheriasis.

Authors:  M A Nesky; E C McDougal; J E Peacock
Journal:  Clin Infect Dis       Date:  2000-09-27       Impact factor: 9.079

7.  Voriconazole treatment for less-common, emerging, or refractory fungal infections.

Authors:  John R Perfect; Kieren A Marr; Thomas J Walsh; Richard N Greenberg; Bertrand DuPont; Juliàn de la Torre-Cisneros; Gudrun Just-Nübling; Haran T Schlamm; Irja Lutsar; Ana Espinel-Ingroff; Elizabeth Johnson
Journal:  Clin Infect Dis       Date:  2003-04-22       Impact factor: 9.079

8.  Voriconazole concentrations in the cerebrospinal fluid and brain tissue of guinea pigs and immunocompromised patients.

Authors:  Irja Lutsar; Sarah Roffey; Peter Troke
Journal:  Clin Infect Dis       Date:  2003-08-07       Impact factor: 9.079

9.  Improving the mouse model for studying the efficacy of voriconazole.

Authors:  John R Graybill; Laura K Najvar; Gloria M Gonzalez; Steve Hernandez; Rosie Bocanegra
Journal:  J Antimicrob Chemother       Date:  2003-05-13       Impact factor: 5.790

10.  Efficacy of voriconazole in treatment of systemic scedosporiosis in neutropenic mice.

Authors:  Javier Capilla; Carolina Serena; F Javier Pastor; Montserrat Ortoneda; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2003-12       Impact factor: 5.191
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  13 in total

1.  Antifungal susceptibilities of the species of the Pseudallescheria boydii complex.

Authors:  Fèlix Gilgado; Carolina Serena; Josep Cano; Josepa Gené; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2006-10-02       Impact factor: 5.191

2.  Molecular phylogeny of the Pseudallescheria boydii species complex: proposal of two new species.

Authors:  Felix Gilgado; Josep Cano; Josepa Gené; Josep Guarro
Journal:  J Clin Microbiol       Date:  2005-10       Impact factor: 5.948

3.  In vitro synergistic interaction between amphotericin B and micafungin against Scedosporium spp.

Authors:  Clara Yustes; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2005-08       Impact factor: 5.191

4.  Experimental murine scedosporiosis: histopathology and azole treatment.

Authors:  M Mar Rodríguez; F Javier Pastor; Valentina Salas; Enrique Calvo; Emilio Mayayo; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2010-06-14       Impact factor: 5.191

Review 5.  Animal Models of Aspergillosis.

Authors:  Guillaume Desoubeaux; Carolyn Cray
Journal:  Comp Med       Date:  2018-04-02       Impact factor: 0.982

Review 6.  Infections caused by Scedosporium spp.

Authors:  Karoll J Cortez; Emmanuel Roilides; Flavio Quiroz-Telles; Joseph Meletiadis; Charalampos Antachopoulos; Tena Knudsen; Wendy Buchanan; Jeffrey Milanovich; Deanna A Sutton; Annette Fothergill; Michael G Rinaldi; Yvonne R Shea; Theoklis Zaoutis; Shyam Kottilil; Thomas J Walsh
Journal:  Clin Microbiol Rev       Date:  2008-01       Impact factor: 26.132

7.  Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients.

Authors:  Peter Troke; Koldo Aguirrebengoa; Carmen Arteaga; David Ellis; Christopher H Heath; Irja Lutsar; Montserrat Rovira; Quoc Nguyen; Monica Slavin; Sharon C A Chen
Journal:  Antimicrob Agents Chemother       Date:  2008-01-22       Impact factor: 5.191

8.  Pharmacodynamics of Voriconazole for Invasive Pulmonary Scedosporiosis.

Authors:  Helen Box; Clara Negri; Joanne Livermore; Sarah Whalley; Adam Johnson; Laura McEntee; Ana Alastruey-Izquierdo; Jacques F Meis; Christopher Thornton; William Hope
Journal:  Antimicrob Agents Chemother       Date:  2018-04-26       Impact factor: 5.191

Review 9.  Mycetoma medical therapy.

Authors:  Oliverio Welsh; Hail Mater Al-Abdely; Mario Cesar Salinas-Carmona; Ahmed Hassan Fahal
Journal:  PLoS Negl Trop Dis       Date:  2014-10-16

10.  Voriconazole in the management of nosocomial invasive fungal infections.

Authors:  Javier Pemán; Miguel Salavert; Emilia Cantón; Isidro Jarque; Eva Romá; Rafael Zaragoza; Angel Viudes; Miguel Gobernado
Journal:  Ther Clin Risk Manag       Date:  2006-06       Impact factor: 2.423
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