| Literature DB >> 14638514 |
Javier Capilla1, Carolina Serena, F Javier Pastor, Montserrat Ortoneda, Josep Guarro.
Abstract
We have evaluated the efficacy of voriconazole (VRC) in a murine model of systemic infection by Scedosporium apiospermum. The survival of mice treated with VRC at 5, 20, or 40 mg/kg/day was greater than that of the control group (P< or =0.0009). VRC reduced the tissue burden in the spleen and brain (P<0.001 in both organs) in comparison with that of the control group.Entities:
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Year: 2003 PMID: 14638514 PMCID: PMC296198 DOI: 10.1128/AAC.47.12.3976-3978.2003
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191