Literature DB >> 20547805

Experimental murine scedosporiosis: histopathology and azole treatment.

M Mar Rodríguez1, F Javier Pastor, Valentina Salas, Enrique Calvo, Emilio Mayayo, Josep Guarro.   

Abstract

The histopathology of clinical isolates of Scedosporium apiospermum, Scedosporium boydii, and Scedosporium aurantiacum in immunosuppressed mice was evaluated. The organs most affected were the brain, kidneys, and spleen. S. aurantiacum produced more tissue damage than the other two species. Amphotericin B (AMB) was ineffective in the treatment of murine infections caused by such isolates, and posaconazole and voriconazole showed efficacy that correlated with the in vitro susceptibility data.

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Year:  2010        PMID: 20547805      PMCID: PMC2935030          DOI: 10.1128/AAC.00046-10

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  21 in total

1.  Disseminated Pseudallescheria boydii infection successfully treated with voriconazole.

Authors:  L G Apostolova; E K Johnson; H P Adams
Journal:  J Neurol Neurosurg Psychiatry       Date:  2005-12       Impact factor: 10.154

2.  Antifungal susceptibilities of the species of the Pseudallescheria boydii complex.

Authors:  Fèlix Gilgado; Carolina Serena; Josep Cano; Josepa Gené; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2006-10-02       Impact factor: 5.191

3.  A novel murine model of cerebral scedosporiosis: lack of efficacy of amphotericin B.

Authors:  Javier Capilla; Emilio Mayayo; Carolina Serena; F Javier Pastor; Josep Guarro
Journal:  J Antimicrob Chemother       Date:  2004-10-27       Impact factor: 5.790

4.  Prevalence and susceptibility testing of new species of pseudallescheria and scedosporium in a collection of clinical mold isolates.

Authors:  Ana Alastruey-Izquierdo; Manuel Cuenca-Estrella; Araceli Monzón; Juan L Rodriguez-Tudela
Journal:  Antimicrob Agents Chemother       Date:  2006-11-13       Impact factor: 5.191

5.  Scedosporium apiospermum mycetoma with bone involvement successfully treated with voriconazole.

Authors:  L Porte; S Khatibi; L El Hajj; S Cassaing; A Berry; P Massip; M D Linas; J F Magnaval; N Sans; B Marchou
Journal:  Trans R Soc Trop Med Hyg       Date:  2006-05-22       Impact factor: 2.184

Review 6.  Infections caused by Scedosporium spp.

Authors:  Karoll J Cortez; Emmanuel Roilides; Flavio Quiroz-Telles; Joseph Meletiadis; Charalampos Antachopoulos; Tena Knudsen; Wendy Buchanan; Jeffrey Milanovich; Deanna A Sutton; Annette Fothergill; Michael G Rinaldi; Yvonne R Shea; Theoklis Zaoutis; Shyam Kottilil; Thomas J Walsh
Journal:  Clin Microbiol Rev       Date:  2008-01       Impact factor: 26.132

7.  Molecular and phenotypic data supporting distinct species statuses for Scedosporium apiospermum and Pseudallescheria boydii and the proposed new species Scedosporium dehoogii.

Authors:  Fèlix Gilgado; Josep Cano; Josepa Gené; Deanna A Sutton; Josep Guarro
Journal:  J Clin Microbiol       Date:  2007-12-12       Impact factor: 5.948

8.  Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients.

Authors:  Peter Troke; Koldo Aguirrebengoa; Carmen Arteaga; David Ellis; Christopher H Heath; Irja Lutsar; Montserrat Rovira; Quoc Nguyen; Monica Slavin; Sharon C A Chen
Journal:  Antimicrob Agents Chemother       Date:  2008-01-22       Impact factor: 5.191

9.  In vitro activities of 35 double combinations of antifungal agents against Scedosporium apiospermum and Scedosporium prolificans.

Authors:  Manuel Cuenca-Estrella; Ana Alastruey-Izquierdo; Laura Alcazar-Fuoli; Leticia Bernal-Martinez; Alicia Gomez-Lopez; Maria J Buitrago; Emilia Mellado; Juan L Rodriguez-Tudela
Journal:  Antimicrob Agents Chemother       Date:  2008-01-14       Impact factor: 5.191

10.  Activities of voriconazole, itraconazole and amphotericin B in vitro against 590 moulds from 323 patients in the voriconazole Phase III clinical studies.

Authors:  Ana Espinel-Ingroff; Elizabeth Johnson; Hans Hockey; Peter Troke
Journal:  J Antimicrob Chemother       Date:  2008-01-25       Impact factor: 5.790

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  6 in total

1.  Evaluation of the efficacies of Amphotericin B, Posaconazole, Voriconazole, and Anidulafungin in a murine disseminated infection by the emerging opportunistic Fungus Sarocladium (Acremonium) kiliense.

Authors:  Fabiola Fernández-Silva; Javier Capilla; Emilio Mayayo; Deanna A Sutton; Pilar Hernández; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2013-10-07       Impact factor: 5.191

2.  Susceptibility and diversity in the therapy-refractory genus scedosporium.

Authors:  M Lackner; F Hagen; J F Meis; A H G Gerrits van den Ende; D Vu; V Robert; J Fritz; T A A Moussa; G S de Hoog
Journal:  Antimicrob Agents Chemother       Date:  2014-07-28       Impact factor: 5.191

3.  Pharmacodynamics of Voriconazole for Invasive Pulmonary Scedosporiosis.

Authors:  Helen Box; Clara Negri; Joanne Livermore; Sarah Whalley; Adam Johnson; Laura McEntee; Ana Alastruey-Izquierdo; Jacques F Meis; Christopher Thornton; William Hope
Journal:  Antimicrob Agents Chemother       Date:  2018-04-26       Impact factor: 5.191

4.  Cytoskeletal Alteration Is an Early Cellular Response in Pulmonary Epithelium Infected with Aspergillus fumigatus Rather than Scedosporium apiospermum.

Authors:  Tapanee Kanjanapruthipong; Passanesh Sukphopetch; Onrapak Reamtong; Duangnate Isarangkul; Watcharamat Muangkaew; Tipparat Thiangtrongjit; Nichapa Sansurin; Kamonpan Fongsodsri; Sumate Ampawong
Journal:  Microb Ecol       Date:  2021-04-22       Impact factor: 4.552

5.  Influence of relevant cystic fibrosis bacteria on Scedosporium apiospermum and Scedosporium boydii growth and viability.

Authors:  Andressa de Jesus Marques; Rodrigo Rollin-Pinheiro; Mariana Ingrid Dutra da Silva Xisto; André Luis Souza Dos Santos; Eliana Barreto-Bergter; Livia Cristina Liporagi-Lopes
Journal:  Braz J Microbiol       Date:  2021-01-13       Impact factor: 2.476

6.  Multilocus Sequence Typing Reveals Extensive Genetic Diversity of the Emerging Fungal Pathogen Scedosporium aurantiacum.

Authors:  Azian Harun; Alex Kan; Katharina Schwabenbauer; Felix Gilgado; Haybrig Perdomo; Carolina Firacative; Heidemarie Losert; Sarimah Abdullah; Sandrine Giraud; Josef Kaltseis; Mark Fraser; Walter Buzina; Michaela Lackner; Christopher C Blyth; Ian Arthur; Johannes Rainer; José F Cano Lira; Josep Guarro Artigas; Kathrin Tintelnot; Monica A Slavin; Christopher H Heath; Jean-Philippe Bouchara; Sharon C A Chen; Wieland Meyer
Journal:  Front Cell Infect Microbiol       Date:  2021-12-27       Impact factor: 5.293

  6 in total

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