| Literature DB >> 1537646 |
L Cid1, G Pararajasegaram, A Sevanian, W Gauderman, J L Romero, G E Marak, N A Rao.
Abstract
The anti-phlogistic effect of dietary vitamin E supplementation on the acute inflammation observed in experimental lens-induced uveitis in Brown Norway rats was studied. The effects of vitamin E were examined using histopathologic parameters as well as by measuring the levels of arachidonic acid metabolites. Histologic examination of the eyes revealed that the vitamin E-deficient animals had the most severe destruction of the retina, while those animals receiving the vitamin E-supplemented diet exhibited the best preservation of the retinal architecture. Levels of arachidonic acid metabolites, as determined by radioimmunoassay, were significantly higher in vitamin E deficient rats as compared with rats on a normal diet.Entities:
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Year: 1992 PMID： 1537646 DOI： 10.1007/bf00917069
Source DB: PubMed Journal: Int Ophthalmol ISSN： 0165-5701 Impact factor: 2.031