Literature DB >> 15345534

Coupling of protein relaxation to ligand binding and migration in myoglobin.

Noam Agmon1.   

Abstract

Protein relaxation, ligand binding, and ligand migration into a hydrophobic cavity in myoglobin are unified by a bounded diffusion model which produces an accurate fit to complex ligand rebinding data over eight decades in time and a 160 K temperature range, in qualitative agreement with time-resolved x-ray crystallography. Protein relaxation operates in a cyclic manner to move the ligand away from the binding site.

Mesh：

Substances：

Year:  2004        PMID： 15345534      PMCID： PMC1304560          DOI： 10.1529/biophysj.104.042929

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  31 in total

1.  A steric mechanism for inhibition of CO binding to heme proteins.

Authors:  G S Kachalova; A N Popov; H D Bartunik
Journal:  Science       Date:  1999-04-16       Impact factor: 47.728

Review 2.  Nitric oxide and myoglobins.

Authors:  Jens K S Møller; Leif H Skibsted
Journal:  Chem Rev       Date:  2002-04       Impact factor: 60.622

3.  Competition with xenon elicits ligand migration and escape pathways in myoglobin.

Authors:  Catherine Tetreau; Yves Blouquit; Eugene Novikov; Eric Quiniou; Daniel Lavalette
Journal:  Biophys J       Date:  2004-01       Impact factor: 4.033

4.  Ligand binding to heme proteins: connection between dynamics and function.

Authors:  P J Steinbach; A Ansari; J Berendzen; D Braunstein; K Chu; B R Cowen; D Ehrenstein; H Frauenfelder; J B Johnson; D C Lamb
Journal:  Biochemistry       Date:  1991-04-23       Impact factor: 3.162

5.  Ligand binding and protein relaxation in heme proteins: a room temperature analysis of NO geminate recombination.

Authors:  J W Petrich; J C Lambry; K Kuczera; M Karplus; C Poyart; J L Martin
Journal:  Biochemistry       Date:  1991-04-23       Impact factor: 3.162

6.  Ligand migration in sperm whale myoglobin.

Authors:  E E Scott; Q H Gibson
Journal:  Biochemistry       Date:  1997-09-30       Impact factor: 3.162

7.  Linkage of functional and structural heterogeneity in proteins: dynamic hole burning in carboxymyoglobin.

Authors:  B F Campbell; M R Chance; J M Friedman
Journal:  Science       Date:  1987-10-16       Impact factor: 47.728

8.  Structural relaxation and nonexponential kinetics of CO-binding to horse myoglobin. Multiple flash photolysis experiments.

Authors:  F Post; W Doster; G Karvounis; M Settles
Journal:  Biophys J       Date:  1993-06       Impact factor: 4.033

9.  Mapping the pathways for O2 entry into and exit from myoglobin.

Authors:  E E Scott; Q H Gibson; J S Olson
Journal:  J Biol Chem       Date:  2000-10-03       Impact factor: 5.157

Review 10.  Emerging roles for myoglobin in the heart.

Authors:  Daniel J Garry; Shane B Kanatous; Pradeep P A Mammen
Journal:  Trends Cardiovasc Med       Date:  2003-04       Impact factor: 6.677
View more
  7 in total

1.  Studying reactive processes with classical dynamics: rebinding dynamics in MbNO.

Authors:  David R Nutt; Markus Meuwly
Journal:  Biophys J       Date:  2005-12-02       Impact factor: 4.033

2.  Deuterium Kinetic Isotope Effects Resolve Low-Temperature Substrate Radical Reaction Pathways and Steps in B12-Dependent Ethanolamine Ammonia-Lyase.

Authors:  Meghan Kohne; Wei Li; Chen Zhu; Kurt Warncke
Journal:  Biochemistry       Date:  2019-08-16       Impact factor: 3.162

3.  Two Dynamical Regimes of the Substrate Radical Rearrangement Reaction in B12-Dependent Ethanolamine Ammonia-Lyase Resolve Contributions of Native Protein Configurations and Collective Configurational Fluctuations to Catalysis.

Authors:  Meghan Kohne; Chen Zhu; Kurt Warncke
Journal:  Biochemistry       Date:  2017-06-15       Impact factor: 3.162

4.  Structure-function relationship in a variant hemoglobin: a combined computational-experimental approach.

Authors:  Matteo Ceccarelli; Paolo Ruggerone; Roberto Anedda; Antonella Fais; Benedetta Era; Maria Carla Sollaino; Marcella Corda; Mariano Casu
Journal:  Biophys J       Date:  2006-07-14       Impact factor: 4.033

5.  Resolution and characterization of contributions of select protein and coupled solvent configurational fluctuations to radical rearrangement catalysis in coenzyme B12-dependent ethanolamine ammonia-lyase.

Authors:  Meghan Kohne; Wei Li; Alina Ionescu; Chen Zhu; Kurt Warncke
Journal:  Methods Enzymol       Date:  2022-01-29       Impact factor: 1.682

Review 6.  Binding and docking interactions of NO, CO and O₂in heme proteins as probed by density functional theory.

Authors:  Vangelis Daskalakis; Constantinos Varotsis
Journal:  Int J Mol Sci       Date:  2009-09-22       Impact factor: 6.208

7.  Internal water and microsecond dynamics in myoglobin.

Authors:  Shuji Kaieda; Bertil Halle
Journal:  J Phys Chem B       Date:  2013-11-19       Impact factor: 2.991
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.