Literature DB >> 1534212

Effectiveness of dehydroepiandrosterone in reduction of cryptosporidial activity in immunosuppressed rats.

K R Rasmussen1, M J Arrowood, M C Healey.   

Abstract

The aim of this study was to evaluate the efficacy of the immunomodulator dehydroepiandrosterone in the treatment of cryptosporidiosis in glucocorticoid-induced immunosuppressed rats. A significant reduction in cryptosporidial activity occurred in treated versus untreated rats as assessed by oocyst shedding intensities and examination of parasite colonization in the small intestine.

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Year:  1992        PMID： 1534212      PMCID： PMC189268          DOI： 10.1128/AAC.36.1.220

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

Review 1.  Role of opportunistic viral infections in AIDS.

Authors:  J A Nelson; P Ghazal; C A Wiley
Journal:  AIDS       Date:  1990-01       Impact factor: 4.177

2.  Isolation of Cryptosporidium oocysts and sporozoites using discontinuous sucrose and isopycnic Percoll gradients.

Authors:  M J Arrowood; C R Sterling
Journal:  J Parasitol       Date:  1987-04       Impact factor: 1.276

3.  Characterization of a dexamethasone-treated rat model of cryptosporidial infection.

Authors:  J E Rehg; M L Hancock; D B Woodmansee
Journal:  J Infect Dis       Date:  1988-12       Impact factor: 5.226

Review 4.  Cryptosporidiosis in animals and humans.

Authors:  S Tzipori
Journal:  Microbiol Rev       Date:  1983-03

5.  Comparison of conventional staining methods and monoclonal antibody-based methods for Cryptosporidium oocyst detection.

Authors:  M J Arrowood; C R Sterling
Journal:  J Clin Microbiol       Date:  1989-07       Impact factor: 5.948

Review 6.  Cryptosporidium and cryptosporidiosis.

Authors:  R Soave; D Armstrong
Journal:  Rev Infect Dis       Date:  1986 Nov-Dec

7.  Human cryptosporidiosis in immunocompetent and immunodeficient persons. Studies of an outbreak and experimental transmission.

Authors:  W L Current; N C Reese; J V Ernst; W S Bailey; M B Heyman; W M Weinstein
Journal:  N Engl J Med       Date:  1983-05-26       Impact factor: 91.245

8.  Characterization of cyclophosphamide-rat model of cryptosporidiosis.

Authors:  J E Rehg; M L Hancock; D B Woodmansee
Journal:  Infect Immun       Date:  1987-11       Impact factor: 3.441

9.  Protection against acute lethal viral infections with the native steroid dehydroepiandrosterone (DHEA).

Authors:  R M Loria; T H Inge; S S Cook; A K Szakal; W Regelson
Journal:  J Med Virol       Date:  1988-11       Impact factor: 2.327

10.  Rat model for human cryptosporidiosis.

Authors:  P Brasseur; D Lemeteil; J J Ballet
Journal:  J Clin Microbiol       Date:  1988-05       Impact factor: 5.948
  10 in total
  5 in total

Review 1.  Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation.

Authors:  Ana Koperniku; Adriana A Garcia; Daria Mochly-Rosen
Journal:  J Med Chem       Date:  2022-03-03       Impact factor: 8.039

2.  Putative anticryptosporidial agents tested with an immunodeficient mouse model.

Authors:  G J Leitch; Q He
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

3.  Glucose-6-phosphate dehydrogenase of trypanosomatids: characterization, target validation, and drug discovery.

Authors:  Shreedhara Gupta; Mariana Igoillo-Esteve; Paul A M Michels; Artur T Cordeiro
Journal:  Mol Biol Int       Date:  2011-04-04

4.  Differential Effects of Naja naja atra Venom on Immune Activity.

Authors:  Jian-Qun Kou; Rong Han; Yin-Li Xu; Xiao-Lan Ding; Shu-Zhi Wang; Cao-Xin Chen; Hong-Zhang Ji; Zhi-Hui Ding; Zheng-Hong Qin
Journal:  Evid Based Complement Alternat Med       Date:  2014-06-12       Impact factor: 2.629

5.  Cryptosporidiosis Modulates the Gut Microbiome and Metabolism in a Murine Infection Model.

Authors:  Avinash V Karpe; Melanie L Hutton; Steven J Mileto; Meagan L James; Chris Evans; Rohan M Shah; Amol B Ghodke; Katie E Hillyer; Suzanne S Metcalfe; Jian-Wei Liu; Tom Walsh; Dena Lyras; Enzo A Palombo; David J Beale
Journal:  Metabolites       Date:  2021-06-11
  5 in total

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