Literature DB >> 8031061

Putative anticryptosporidial agents tested with an immunodeficient mouse model.

G J Leitch1, Q He.   

Abstract

Lasalocid, sinefungin, and dehydroepiandrosterone were tested for anticryptosporidial activity with an immunodeficient mouse model at doses that have been reported effective when tested with immunosuppressed rodent models. Small but significant reductions in oocyst excretion were only observed under some conditions with lasalocid and dehydroepiandrosterone, but sinefungin had no effect.

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Year:  1994        PMID： 8031061      PMCID： PMC284557          DOI： 10.1128/AAC.38.4.865

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  Effectiveness of dehydroepiandrosterone in reduction of cryptosporidial activity in immunosuppressed rats.

Authors:  K R Rasmussen; M J Arrowood; M C Healey
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

2.  Chronic Cryptosporidium parvum infections in congenitally immunodeficient SCID and nude mice.

Authors:  J R Mead; M J Arrowood; R W Sidwell; M C Healey
Journal:  J Infect Dis       Date:  1991-06       Impact factor: 5.226

Review 3.  Cryptosporidiosis.

Authors:  W L Current; L S Garcia
Journal:  Clin Lab Med       Date:  1991-12       Impact factor: 1.935

4.  New mouse models for chronic Cryptosporidium infection in immunodeficient hosts.

Authors:  B L Ungar; J A Burris; C A Quinn; F D Finkelman
Journal:  Infect Immun       Date:  1990-04       Impact factor: 3.441

5.  Isolation of Cryptosporidium oocysts and sporozoites using discontinuous sucrose and isopycnic Percoll gradients.

Authors:  M J Arrowood; C R Sterling
Journal:  J Parasitol       Date:  1987-04       Impact factor: 1.276

Review 6.  Manipulation of the immune response in parasitic infections.

Authors:  J G Howard
Journal:  Parasitology       Date:  1984-08       Impact factor: 3.234

7.  Anticryptosporidial activity is associated with specific sulfonamides in immunosuppressed rats.

Authors:  J E Rehg
Journal:  J Parasitol       Date:  1991-04       Impact factor: 1.276

8.  Transplantability of human lymphoid cell line, lymphoma, and leukemia in splenectomized and/or irradiated nude mice.

Authors:  S Watanabe; Y Shimosato; M Kuroki; Y Sato; T Nakajima
Journal:  Cancer Res       Date:  1980-07       Impact factor: 12.701

9.  Effects of dehydroepiandrosterone in immunosuppressed rats infected with Cryptosporidium parvum.

Authors:  K R Rasmussen; E G Martin; M C Healey
Journal:  J Parasitol       Date:  1993-06       Impact factor: 1.276

Review 10.  Cryptosporidiosis in perspective.

Authors:  S Tzipori
Journal:  Adv Parasitol       Date:  1988       Impact factor: 3.870
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  4 in total

1.  Reactive nitrogen and oxygen species ameliorate experimental cryptosporidiosis in the neonatal BALB/c mouse model.

Authors:  G J Leitch; Q He
Journal:  Infect Immun       Date:  1999-11       Impact factor: 3.441

2.  Evaluation of maduramicin and alborixin in a SCID mouse model of chronic cryptosporidiosis.

Authors:  J R Mead; X You; J E Pharr; Y Belenkaya; M J Arrowood; M T Fallon; R F Schinazi
Journal:  Antimicrob Agents Chemother       Date:  1995-04       Impact factor: 5.191

3.  Arginine-derived nitric oxide reduces fecal oocyst shedding in nude mice infected with Cryptosporidium parvum.

Authors:  G J Leitch; Q He
Journal:  Infect Immun       Date:  1994-11       Impact factor: 3.441

4.  Global distribution, public health and clinical impact of the protozoan pathogen cryptosporidium.

Authors:  Lorenza Putignani; Donato Menichella
Journal:  Interdiscip Perspect Infect Dis       Date:  2010-07-14
  4 in total

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