Literature DB >> 15339201

Allergic rhinitis in children : diagnosis and management strategies.

William E Berger1.   

Abstract

The incidence of allergic rhinitis has been increasing for the last few decades, in keeping with the rising incidence of atopy worldwide. Allergic rhinitis has a prevalence of up to 40% in children, although it frequently goes unrecognized and untreated. This can have enormous negative consequences, particularly in children, since it is associated with numerous complications and comorbidities that have a significant health impact on quality of life. In fact, allergic rhinitis is considered to be a risk factor for asthma. There are numerous signs of allergic rhinitis, particularly in children, that can alert an observant clinician to its presence. Children with severe allergic rhinitis often have facial manifestations of itching and obstructed breathing, including a gaping mouth, chapped lips, evidence of sleep deprivation, a long face, dental malloclusions, and the allergic shiner, allergic salute, or allergic crease. The medical history is extremely important as it can reveal information regarding a family history of atopy and the progression of atopy in the child. It is also important to identify the specific triggers of allergic rhinitis, because one of the keys to successful management is the avoidance of triggers. A tripartite treatment strategy that embraces environmental control, immunotherapy, and pharmacologic treatment is the most comprehensive approach. Immunotherapy has come to be viewed as potentially prophylactic, capable of altering the course of allergic rhinitis. The most recent guidelines for the management of allergic rhinitis issued by the WHO recommend a tiered approach that integrates diagnosis and treatment, in which allergic rhinitis is subclassified both by frequency, as either intermittent or persistent, and by severity, as either mild or moderate to severe. Oral or topical antihistamines and intranasal corticosteroids are the mainstay of pharmacologic therapy for allergic rhinitis, depending upon its severity, and several agents have been approved for use in children aged 5 years old and younger.

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Year:  2004        PMID: 15339201     DOI: 10.2165/00148581-200406040-00003

Source DB:  PubMed          Journal:  Paediatr Drugs        ISSN: 1174-5878            Impact factor:   3.022


  236 in total

1.  International Study of Asthma and Allergies in Childhood: validation of the rhinitis symptom questionnaire and prevalence of rhinitis in schoolchildren in São Paulo, Brazil.

Authors:  A T Vanna; E Yamada; L K Arruda; C K Naspitz; D Solé
Journal:  Pediatr Allergy Immunol       Date:  2001-04       Impact factor: 6.377

2.  Immunotherapy decreases antigen-induced eosinophil cell migration into the nasal cavity.

Authors:  M J Furin; P S Norman; P S Creticos; D Proud; A Kagey-Sobotka; L M Lichtenstein; R M Naclerio
Journal:  J Allergy Clin Immunol       Date:  1991-07       Impact factor: 10.793

3.  Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study).

Authors:  Christian Möller; Sten Dreborg; Hosne A Ferdousi; Susanne Halken; Arne Høst; Lars Jacobsen; Antti Koivikko; Dieter Y Koller; Bodo Niggemann; Lene A Norberg; Radvan Urbanek; Erkka Valovirta; Ulrich Wahn
Journal:  J Allergy Clin Immunol       Date:  2002-02       Impact factor: 10.793

Review 4.  Clinical pharmacology of new histamine H1 receptor antagonists.

Authors:  F E Simons; K J Simons
Journal:  Clin Pharmacokinet       Date:  1999-05       Impact factor: 6.447

5.  Improvement of bronchial hyperresponsiveness in asthmatic children treated for concomitant sinusitis.

Authors:  C A Oliveira; D Solé; C K Naspitz; G S Rachelefsky
Journal:  Ann Allergy Asthma Immunol       Date:  1997-07       Impact factor: 6.347

Review 6.  H1-antagonists as a tool in clarifying the pathophysiology of nasal allergy.

Authors:  U Pipkorn
Journal:  Clin Exp Allergy       Date:  1990-08       Impact factor: 5.018

7.  Transient sensitization to house-dust mites: a study on the influence of mite exposure and sex.

Authors:  M Wickman; J Korsgaard
Journal:  Allergy       Date:  1996-07       Impact factor: 13.146

8.  Development of seasonal allergic rhinitis during the first 7 years of life.

Authors:  M Kulig; U Klettke; V Wahn; J Forster; C P Bauer; U Wahn
Journal:  J Allergy Clin Immunol       Date:  2000-11       Impact factor: 10.793

Review 9.  Management of allergic rhinitis with a combination antihistamine/anti-inflammatory agent.

Authors:  P Lieberman
Journal:  J Allergy Clin Immunol       Date:  1999-03       Impact factor: 10.793

10.  Topical corticosteroids and nasal reactivity.

Authors:  J A Wihl
Journal:  Eur J Respir Dis Suppl       Date:  1982
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  19 in total

Review 1.  Optimal management of nasal congestion caused by allergic rhinitis in children: safety and efficacy of medical treatments.

Authors:  Glenis Scadding
Journal:  Paediatr Drugs       Date:  2008       Impact factor: 3.022

2.  Atypical "allergic crease".

Authors:  Yuval Ramot; Alex Maly; Abraham Zlotogorski; Krassimira Nanova
Journal:  J Dermatol Case Rep       Date:  2010-12-19

3.  Desloratadine dose selection in children aged 6 months to 2 years: comparison of population pharmacokinetics between children and adults.

Authors:  Samir K Gupta; Bhavna Kantesaria; Christopher Banfield; Zaiqi Wang
Journal:  Br J Clin Pharmacol       Date:  2007-02-23       Impact factor: 4.335

Review 4.  Comparative analysis of allergic rhinitis in children and adults.

Authors:  Adriana Izquierdo-Domínguez; Antonio L Valero; Joaquim Mullol
Journal:  Curr Allergy Asthma Rep       Date:  2013-04       Impact factor: 4.806

5.  The pathophysiology, diagnosis and treatment of allergic rhinitis.

Authors:  Yang-Gi Min
Journal:  Allergy Asthma Immunol Res       Date:  2010-03-24       Impact factor: 5.764

6.  Clinical efficacy and safety of a combined loratadine-betamethasone oral solution in the treatment of severe pediatric perennial allergic rhinitis.

Authors:  Teolinda Mendoza de Morales; Francis Sánchez
Journal:  World Allergy Organ J       Date:  2009-04       Impact factor: 4.084

7.  Variability of histamine pharmacodynamic response in children with allergic rhinitis.

Authors:  Bridgette L Jones; Gregory Kearns; Kathleen A Neville; Catherine M T Sherwin; Michael M G Spigarelli; J Steven Leeder
Journal:  J Clin Pharmacol       Date:  2013-05-16       Impact factor: 3.126

Review 8.  Mometasone furoate: a review of its intranasal use in allergic rhinitis.

Authors:  Claudine M Baldwin; Lesley J Scott
Journal:  Drugs       Date:  2008       Impact factor: 9.546

9.  Allergic rhinitis induces anxiety-like behavior and altered social interaction in rodents.

Authors:  Leonardo H Tonelli; Morgan Katz; Colleen E Kovacsics; Todd D Gould; Belzora Joppy; Akina Hoshino; Gloria Hoffman; Hirsh Komarow; Teodor T Postolache
Journal:  Brain Behav Immun       Date:  2009-03-05       Impact factor: 7.217

10.  Safety and tolerability of fluticasone furoate nasal spray once daily in paediatric patients aged 6-11 years with allergic rhinitis: subanalysis of three randomized, double-blind, placebo-controlled, multicentre studies.

Authors:  Eli O Meltzer; Ita Tripathy; Jorge F Máspero; Wei Wu; Ed Philpot
Journal:  Clin Drug Investig       Date:  2009       Impact factor: 2.859

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