| Literature DB >> 15321687 |
M Cruz Martín1, María Fernández, José M Martin-Alonso, Francisco Parra, José A Boga, Miguel A Alvarez.
Abstract
A food-grade strain with nisRK stably integrated into the genome, was constructed in order to implement the nisin-controlled expression system (NICE) in Lactobacillus casei ATCC393. Expression of beta-glucuronidase (gus) reporter gene was employed to optimize the system, which has been successfully used to produce the main antigenic protein from Norwalk virus, opening new perspectives for producing edible vaccines.Entities:
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Year: 2004 PMID： 15321687 DOI： 10.1016/j.femsle.2004.07.002
Source DB: PubMed Journal: FEMS Microbiol Lett ISSN： 0378-1097 Impact factor: 2.742