Literature DB >> 21257814

Integrative expression system for delivery of antibody fragments by lactobacilli.

M Cruz Martín1, Neha Pant, Victor Ladero, Gökçe Günaydin, Kasper Krogh Andersen, Beatriz Alvarez, Noelia Martínez, Miguel A Alvarez, Lennart Hammarström, Harold Marcotte.   

Abstract

A series of expression cassettes which mediate secretion or surface display of antibody fragments was stably integrated in the chromosome of Lactobacillus paracasei. L. paracasei producing surface-anchored variable domain of llama heavy chain (VHH) (ARP1) directed against rotavirus showed efficient binding to rotavirus and protection in the mouse model of rotavirus infection.

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Year:  2011        PMID： 21257814      PMCID： PMC3067310          DOI： 10.1128/AEM.02690-10

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  18 in total

1.  Generation of food-grade recombinant lactic acid bacterium strains by site-specific recombination.

Authors:  M C Martín; J C Alonso; J E Suárez; M A Alvarez
Journal:  Appl Environ Microbiol       Date:  2000-06       Impact factor: 4.792

2.  The aggregation-promoting factor of Lactobacillus crispatus M247 and its genetic locus.

Authors:  H Marcotte; S Ferrari; C Cesena; L Hammarström; L Morelli; G Pozzi; M R Oggioni
Journal:  J Appl Microbiol       Date:  2004       Impact factor: 3.772

3.  Identification and characterization of novel surface proteins in Lactobacillus johnsonii and Lactobacillus gasseri.

Authors:  Marco Ventura; Ivana Jankovic; D Carey Walker; R David Pridmore; Ralf Zink
Journal:  Appl Environ Microbiol       Date:  2002-12       Impact factor: 4.792

4.  Surface display of foreign epitopes on the Lactobacillus brevis S-layer.

Authors:  Silja Avall-Jääskeläinen; Kari Kylä-Nikkilä; Minna Kahala; Terhi Miikkulainen-Lahti; Airi Palva
Journal:  Appl Environ Microbiol       Date:  2002-12       Impact factor: 4.792

5.  Nisin-controlled expression of Norwalk virus VP60 protein in Lactobacillus casei.

Authors:  M Cruz Martín; María Fernández; José M Martin-Alonso; Francisco Parra; José A Boga; Miguel A Alvarez
Journal:  FEMS Microbiol Lett       Date:  2004-08-15       Impact factor: 2.742

6.  Contribution of aggregation-promoting factor to maintenance of cell shape in Lactobacillus gasseri 4B2.

Authors:  Ivana Jankovic; Marco Ventura; Valerie Meylan; Martine Rouvet; Marina Elli; Ralf Zink
Journal:  J Bacteriol       Date:  2003-06       Impact factor: 3.490

7.  Identification and characterization of the novel LysM domain-containing surface protein Sep from Lactobacillus fermentum BR11 and its use as a peptide fusion partner in Lactobacillus and Lactococcus.

Authors:  Mark S Turner; Louise M Hafner; Terry Walsh; Philip M Giffard
Journal:  Appl Environ Microbiol       Date:  2004-06       Impact factor: 4.792

8.  In situ delivery of passive immunity by lactobacilli producing single-chain antibodies.

Authors:  Carina Krüger; Yanzhong Hu; Qiang Pan; Harold Marcotte; Anna Hultberg; Dipu Delwar; Philip J van Dalen; Peter H Pouwels; Rob J Leer; Charles G Kelly; Craig van Dollenweerd; Julian K Ma; Lennart Hammarström
Journal:  Nat Biotechnol       Date:  2002-07       Impact factor: 54.908

9.  The site-specific recombination system of the Lactobacillus species bacteriophage A2 integrates in gram-positive and gram-negative bacteria.

Authors:  M A Alvarez; M Herrero; J E Suárez
Journal:  Virology       Date:  1998-10-10       Impact factor: 3.616

Review 10.  Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria.

Authors:  Jerry M Wells; Annick Mercenier
Journal:  Nat Rev Microbiol       Date:  2008-05       Impact factor: 60.633
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  21 in total

1.  Generation of food-grade recombinant Lactobacillus casei delivering Myxococcus xanthus prolyl endopeptidase.

Authors:  Patricia Alvarez-Sieiro; Maria Cruz Martin; Begoña Redruello; Beatriz Del Rio; Victor Ladero; Brad A Palanski; Chaitan Khosla; Maria Fernandez; Miguel A Alvarez
Journal:  Appl Microbiol Biotechnol       Date:  2014-04-22       Impact factor: 4.813

2.  Monoclonal and Single Domain Antibodies Targeting β-Integrin Subunits Block Sexual Transmission of HIV-1 in In Vitro and In Vivo Model Systems.

Authors:  Janet Tai Guedon; Kun Luo; Hong Zhang; Richard B Markham
Journal:  J Acquir Immune Defic Syndr       Date:  2015-07-01       Impact factor: 3.731

Review 3.  Engineering commensal bacteria for prophylaxis against infection.

Authors:  Yih-Lin Goh; HongFei He; John C March
Journal:  Curr Opin Biotechnol       Date:  2012-03-28       Impact factor: 9.740

4.  Directed chromosomal integration and expression of the reporter gene gusA3 in Lactobacillus acidophilus NCFM.

Authors:  Grace L Douglas; Todd R Klaenhammer
Journal:  Appl Environ Microbiol       Date:  2011-08-26       Impact factor: 4.792

5.  An Exopolysaccharide-Deficient Mutant of Lactobacillus rhamnosus GG Efficiently Displays a Protective Llama Antibody Fragment against Rotavirus on Its Surface.

Authors:  Beatriz Álvarez; Kasper Krogh-Andersen; Christian Tellgren-Roth; Noelia Martínez; Gökçe Günaydın; Yin Lin; M Cruz Martín; Miguel A Álvarez; Lennart Hammarström; Harold Marcotte
Journal:  Appl Environ Microbiol       Date:  2015-06-19       Impact factor: 4.792

6.  Blocking HIV-1 Infection by Chromosomal Integrative Expression of Human CD4 on the Surface of Lactobacillus acidophilus ATCC 4356.

Authors:  Wenzhong Wei; Joshua Wiggins; Duoyi Hu; Vladimir Vrbanac; Dane Bowder; Michael Mellon; Andrew Tager; Joseph Sodroski; Shi-Hua Xiang
Journal:  J Virol       Date:  2019-04-03       Impact factor: 5.103

7.  Neutralization of Clostridium difficile Toxin B Mediated by Engineered Lactobacilli That Produce Single-Domain Antibodies.

Authors:  Kasper Krogh Andersen; Nika M Strokappe; Anna Hultberg; Kai Truusalu; Imbi Smidt; Raik-Hiio Mikelsaar; Marika Mikelsaar; Theo Verrips; Lennart Hammarström; Harold Marcotte
Journal:  Infect Immun       Date:  2015-11-16       Impact factor: 3.441

8.  Recombinant monovalent llama-derived antibody fragments (VHH) to rotavirus VP6 protect neonatal gnotobiotic piglets against human rotavirus-induced diarrhea.

Authors:  Celina G Vega; Marina Bok; Anastasia N Vlasova; Kuldeep S Chattha; Silvia Gómez-Sebastián; Carmen Nuñez; Carmen Alvarado; Rodrigo Lasa; José M Escribano; Lorena L Garaicoechea; Fernando Fernandez; Karin Bok; Andrés Wigdorovitz; Linda J Saif; Viviana Parreño
Journal:  PLoS Pathog       Date:  2013-05-02       Impact factor: 6.823

Review 9.  Therapeutic Applications of Functional Nanomaterials for Prostatitis.

Authors:  Chun-Ping Liu; Zi-De Chen; Zi-Yan Ye; Dong-Yue He; Yue Dang; Zhe-Wei Li; Lei Wang; Miao Ren; Zhi-Jin Fan; Hong-Xing Liu
Journal:  Front Pharmacol       Date:  2021-05-28       Impact factor: 5.810

10.  Inhibition of HIV and HSV infection by vaginal lactobacilli in vitro and in vivo.

Authors:  Rezvan Zabihollahi; Elahe Motevaseli; Seyed Mehdi Sadat; Ali Reza Azizi-Saraji; Sogol Asaadi-Dalaie; Mohammad Hossein Modarressi
Journal:  Daru       Date:  2012-10-15       Impact factor: 3.117
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