Literature DB >> 15304633

Modeling the heart.

Denis Noble1.   

Abstract

Models of the heart have been developed since 1960, starting with the discovery and modeling of potassium channels. The first models of calcium balance were made in the 1980s and have now reached a high degree of physiological detail. During the 1990s, these cell models were incorporated into anatomically detailed tissue and organ models.

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Year:  2004        PMID： 15304633     DOI： 10.1152/physiol.00004.2004

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  9 in total

1.  [Virtual microscopy in systems pathology].

Authors:  N Grabe
Journal:  Pathologe       Date:  2008-11       Impact factor: 1.011

2.  A multiformalism and multiresolution modelling environment: application to the cardiovascular system and its regulation.

Authors:  Alfredo I Hernández; Virginie Le Rolle; Antoine Defontaine; Guy Carrault
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2009-12-13       Impact factor: 4.226

3.  Silicon dreams of cells into symbols.

Authors:  Jeremy Gunawardena
Journal:  Nat Biotechnol       Date:  2012-09       Impact factor: 54.908

Review 4.  Modeling Ca2+ signaling in the microcirculation: intercellular communication and vasoreactivity.

Authors:  Adam Kapela; Sridevi Nagaraja; Jaimit Parikh; Nikolaos M Tsoukias
Journal:  Crit Rev Biomed Eng       Date:  2011

Review 5.  Cardiac models in drug discovery and development: a review.

Authors:  Robert K Amanfu; Jeffrey J Saucerman
Journal:  Crit Rev Biomed Eng       Date:  2011

Review 6.  Calcium dynamics and signaling in vascular regulation: computational models.

Authors:  Nikolaos Michael Tsoukias
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2011 Jan-Feb

Review 7.  In vitro models of proarrhythmia.

Authors:  C L Lawrence; C E Pollard; T G Hammond; J-P Valentin
Journal:  Br J Pharmacol       Date:  2008-06-02       Impact factor: 8.739

Review 8.  Recent developments in using mechanistic cardiac modelling for drug safety evaluation.

Authors:  Mark R Davies; Ken Wang; Gary R Mirams; Antonello Caruso; Denis Noble; Antje Walz; Thierry Lavé; Franz Schuler; Thomas Singer; Liudmila Polonchuk
Journal:  Drug Discov Today       Date:  2016-02-15       Impact factor: 7.851

Review 9.  Big data need big theory too.

Authors:  Peter V Coveney; Edward R Dougherty; Roger R Highfield
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2016-11-13       Impact factor: 4.226
  9 in total

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