Literature DB >> 15291557

A new class of chiral pyrrolidine-pyridine conjugate base catalysts for use in asymmetric Michael addition reactions.

Takaaki Ishii1, Shingo Fujioka, Yusuke Sekiguchi, Hiyoshizo Kotsuki.   

Abstract

Direct catalytic asymmetric Michael addition reactions of ketones to nitroolefins using newly developed chiral pyrrolidine-pyridine conjugate bases as catalysts are described. The desired 1,4-adducts are obtained in excellent yields with high enantio- and diastereoselectivities.

Entities:  

Year:  2004        PMID： 15291557     DOI： 10.1021/ja046871g

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  9 in total

1.  Fast and selective modification of thiol proteins/peptides by N-(phenylseleno)phthalimide.

Authors:  Zhengfang Wang; Yun Zhang; Hao Zhang; Peter B Harrington; Hao Chen
Journal:  J Am Soc Mass Spectrom       Date:  2012-01-06       Impact factor: 3.109

2.  Silica gel-immobilized multidisciplinary materials applicable in stereoselective organocatalysis and HPLC separation.

Authors:  J Tůma; M Kohout
Journal:  RSC Adv       Date:  2018-01-03       Impact factor: 4.036

3.  Synthesis of Prolinal Dithioacetals as Catalysts for the Highly Stereoselective Michael Addition of Ketones and Aldehydes to beta-Nitrostyrenes.

Authors:  Tanmay Mandal; Cong-Gui Zhao
Journal:  Tetrahedron Lett       Date:  2007       Impact factor: 2.415

4.  Synthesis of new chiral amines with a cyclic 1,2-diacetal skeleton derived from (2R, 3R)-(+)-tartaric acid.

Authors:  M Teresa Barros; Ana Maria Faísca Phillips
Journal:  Molecules       Date:  2006-03-17       Impact factor: 4.411

5.  (S)-2-Amino-1-(pyrrolidinium-2-ylmeth-yl)pyridinium dibromide.

Authors:  Yifeng Wang; Shuai Zhang; Aibao Xia; Shuping Luo; Danqian Xu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-01-18

6.  (S)-2-(Pyrrolidinium-2-ylmethyl-sulfan-yl)pyridinium dibromide.

Authors:  Shuai Zhang; Yifeng Wang; Aibao Xia; Shuping Luo
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-05-24

7.  Synthesis and properties of chiral thioureas bearing an additional function at a remote position tethered by a 1,5-disubstituted triazole.

Authors:  Kiyosei Takasu; Takumi Azuma; Iderbat Enkhtaivan; Yoshiji Takemoto
Journal:  Molecules       Date:  2010-11-15       Impact factor: 4.411

8.  Metal-free, room temperature, acid-K2S2O8 mediated method for the nitration of olefins: an easy approach for the synthesis of nitroolefins.

Authors:  Srinivas Ambala; Rohit Singh; Maninder Singh; Pankaj Singh Cham; Ria Gupta; Gurunadham Munagala; Kushalava Reddy Yempalla; Ram A Vishwakarma; Parvinder Pal Singh
Journal:  RSC Adv       Date:  2019-09-25       Impact factor: 4.036

9.  Enantioselective Michael reaction of anthrone catalyzed by chiral tetraoxacalix[2]arene[2]triazine derivatives.

Authors:  Hayriye Nevin Genc
Journal:  RSC Adv       Date:  2019-07-05       Impact factor: 4.036
  9 in total

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