| Literature DB >> 15291544 |
Caroline Crey-Desbiolles1, Jean Lhomme, Pascal Dumy, Mitsuharu Kotera.
Abstract
A new photocleavable 2'-deoxyadenosine mimic, 3-nitro-3-deaza-2'-deoxyadenosine (NidA), was prepared and introduced into DNA fragments via its 6-O-trimethylphenyl precursor phophoramidite. Photocleavage of the resulting oligonucleotide is highly efficient in single and double strands. Hybridization properties of NidA are very similar to those of deoxyadenosine.Entities:
Mesh：
Substances：
Year: 2004 PMID： 15291544 DOI： 10.1021/ja047976m
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419