RATIONALE AND OBJECTIVES: To compare the diagnostic accuracy of the Fischer Senoscan Digital Mammography System with that of standard screen-film mammography in a population of women presenting for screening or diagnostic mammography. MATERIALS AND METHODS: Enrollment of patients took place at six different breast-imaging centers between 1997 and 1999. A total of 247 cases were selected for inclusion in the final reader study. All known cancer cases were included (111) from all six participating sites representing 45% of the total cases. The remaining 136 cases (55%) were randomly selected from all available benign or negative cases from three of the six sites. A complete case consisted of both a (unilateral or bilateral) digital and screen-film mammogram of the same patient. Eight radiologists interpreted the cases in laser-printed digital and screen-film hardcopy formats. The study was designed to detect differences of 0.05 in the ROC area under the curve (AUC) between digital and screen-film radiologist interpretation performance. RESULTS: The average AUC for the Senoscan digital was 0.715 for the 8 readers. The average AUC for screen-film was 0.765. The difference AUC of -0.05 falls within the 95% confidence interval (-0.101, 0.002). The average sensitivity was 66% and specificity 67% for SenoScan full-field digital mammography. The average screen-film mammography sensitivity and specificity were 74% and 60%, respectively. CONCLUSION: No statistically significant difference in diagnostic accuracy between the Fischer Senoscan and screen-film mammography was detected in this study.
RATIONALE AND OBJECTIVES: To compare the diagnostic accuracy of the Fischer Senoscan Digital Mammography System with that of standard screen-film mammography in a population of women presenting for screening or diagnostic mammography. MATERIALS AND METHODS: Enrollment of patients took place at six different breast-imaging centers between 1997 and 1999. A total of 247 cases were selected for inclusion in the final reader study. All known cancer cases were included (111) from all six participating sites representing 45% of the total cases. The remaining 136 cases (55%) were randomly selected from all available benign or negative cases from three of the six sites. A complete case consisted of both a (unilateral or bilateral) digital and screen-film mammogram of the same patient. Eight radiologists interpreted the cases in laser-printed digital and screen-film hardcopy formats. The study was designed to detect differences of 0.05 in the ROC area under the curve (AUC) between digital and screen-film radiologist interpretation performance. RESULTS: The average AUC for the Senoscan digital was 0.715 for the 8 readers. The average AUC for screen-film was 0.765. The difference AUC of -0.05 falls within the 95% confidence interval (-0.101, 0.002). The average sensitivity was 66% and specificity 67% for SenoScan full-field digital mammography. The average screen-film mammography sensitivity and specificity were 74% and 60%, respectively. CONCLUSION: No statistically significant difference in diagnostic accuracy between the Fischer Senoscan and screen-film mammography was detected in this study.
Authors: Brandon D Gallas; Heang-Ping Chan; Carl J D'Orsi; Lori E Dodd; Maryellen L Giger; David Gur; Elizabeth A Krupinski; Charles E Metz; Kyle J Myers; Nancy A Obuchowski; Berkman Sahiner; Alicia Y Toledano; Margarita L Zuley Journal: Acad Radiol Date: 2012-02-03 Impact factor: 3.173
Authors: Jun Ge; Lubomir M Hadjiiski; Berkman Sahiner; Jun Wei; Mark A Helvie; Chuan Zhou; Heang-Ping Chan Journal: Phys Med Biol Date: 2007-01-23 Impact factor: 3.609
Authors: Jun Wei; Lubomir M Hadjiiski; Berkman Sahiner; Heang-Ping Chan; Jun Ge; Marilyn A Roubidoux; Mark A Helvie; Chuan Zhou; Yi-Ta Wu; Chintana Paramagul; Yiheng Zhang Journal: Acad Radiol Date: 2007-06 Impact factor: 3.173
Authors: R Edward Hendrick; Elodia B Cole; Etta D Pisano; Suddhasatta Acharyya; Helga Marques; Michael A Cohen; Roberta A Jong; Gordon E Mawdsley; Kalpana M Kanal; Carl J D'Orsi; Murray Rebner; Constantine Gatsonis Journal: Radiology Date: 2008-04 Impact factor: 11.105
Authors: Hui Li; Maryellen L Giger; Yading Yuan; Weijie Chen; Karla Horsch; Li Lan; Andrew R Jamieson; Charlene A Sennett; Sanaz A Jansen Journal: Acad Radiol Date: 2008-11 Impact factor: 3.173