Literature DB >> 15273136

Effect of pH on the in vitro activities of amphotericin B, itraconazole, and flucytosine against Aspergillus isolates.

D T A Te Dorsthorst1, J W Mouton, C J P van den Beukel, H A L van der Lee, J F G M Meis, P E Verweij.   

Abstract

The in vitro susceptibilities of 21 Aspergillus isolates were tested against three antifungal agents in RPMI 1640 and yeast nitrogen base at pH 5.0 and 7.0 by a broth microdilution format of the NCCLS method. The MICs of amphotericin B and itraconazole were higher, while those of flucytosine were lower, at pH 5.0 than at pH 7.0. The poor correlation between in vitro results and clinical outcome could be due to a difference in pH between the in vitro susceptibility test and at the site of infection.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15273136      PMCID： PMC478550          DOI： 10.1128/AAC.48.8.3147-3150.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

Review 1.  Antifungal susceptibility testing: practical aspects and current challenges.

Authors:  J H Rex; M A Pfaller; T J Walsh; V Chaturvedi; A Espinel-Ingroff; M A Ghannoum; L L Gosey; F C Odds; M G Rinaldi; D J Sheehan; D W Warnock
Journal:  Clin Microbiol Rev       Date:  2001-10       Impact factor: 26.132

Review 2.  Clinical, cellular, and molecular factors that contribute to antifungal drug resistance.

Authors:  T C White; K A Marr; R A Bowden
Journal:  Clin Microbiol Rev       Date:  1998-04       Impact factor: 26.132

3.  Establishment of an experimental model of a Staphylococcus aureus abscess in mice by use of dextran and gelatin microcarriers.

Authors:  C W Ford; J C Hamel; D Stapert; R J Yancey
Journal:  J Med Microbiol       Date:  1989-04       Impact factor: 2.472

4.  Effects of pH on the activity of ketoconazole against Candida albicans.

Authors:  H Minagawa; K Kitaura; N Nakamizo
Journal:  Antimicrob Agents Chemother       Date:  1983-01       Impact factor: 5.191

5.  Antifungal relative inhibition factors: BAY l-9139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 14-4767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared in vitro with nine established antifungal agents.

Authors:  F C Odds; C E Webster; A B Abbott
Journal:  J Antimicrob Chemother       Date:  1984-08       Impact factor: 5.790

6.  Flucytosine and cryptococcosis: which in vitro test is the best predictor of outcome?

Authors:  M A Viviani; M C Esposto; M Cogliati; A M Tortorano
Journal:  J Chemother       Date:  2003-04       Impact factor: 1.714

7.  The peritoneal environment during infection. The effect of monomicrobial and polymicrobial bacteria on pO2 and pH.

Authors:  R G Sawyer; M D Spengler; R B Adams; T L Pruett
Journal:  Ann Surg       Date:  1991-03       Impact factor: 12.969
  7 in total
  14 in total

1.  Genetic Diversity and In Vitro Antifungal Susceptibility of 200 Clinical and Environmental Aspergillus flavus Isolates.

Authors:  Mojtaba Taghizadeh-Armaki; Mohammad Taghi Hedayati; Saham Ansari; Saeed Mahdavi Omran; Sasan Saber; Haleh Rafati; Jan Zoll; Henrich A van der Lee; Willem J G Melchers; Paul E Verweij; Seyedmojtaba Seyedmousavi
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191

2.  Effect of amphotericin B and micafungin combination on survival, histopathology, and fungal burden in experimental aspergillosis in the p47phox-/- mouse model of chronic granulomatous disease.

Authors:  Carly G Dennis; William R Greco; Yseult Brun; Richard Youn; Harry K Slocum; Ralph J Bernacki; Russell Lewis; Nathan Wiederhold; Steven M Holland; Ruta Petraitiene; Thomas J Walsh; Brahm H Segal
Journal:  Antimicrob Agents Chemother       Date:  2006-02       Impact factor: 5.191

3.  In vitro activities at pH 5.0 and pH 7.0 and in vivo efficacy of flucytosine against Aspergillus fumigatus.

Authors:  Paul E Verweij; Debbie T A Te Dorsthorst; Willem H P Janssen; Jacques F G M Meis; Johan W Mouton
Journal:  Antimicrob Agents Chemother       Date:  2008-09-15       Impact factor: 5.191

4.  Efficacy and pharmacodynamics of flucytosine monotherapy in a nonneutropenic murine model of invasive aspergillosis.

Authors:  D T A te Dorsthorst; P E Verweij; J F G M Meis; J W Mouton
Journal:  Antimicrob Agents Chemother       Date:  2005-10       Impact factor: 5.191

5.  Relationship between in vitro activities of amphotericin B and flucytosine and pH for clinical yeast and mold isolates.

Authors:  D T A te Dorsthorst; P E Verweij; J F G M Meis; J W Mouton
Journal:  Antimicrob Agents Chemother       Date:  2005-08       Impact factor: 5.191

6.  Cryptic species and azole resistance in the Aspergillus niger complex.

Authors:  Susan J Howard; Elizabeth Harrison; Paul Bowyer; Janos Varga; David W Denning
Journal:  Antimicrob Agents Chemother       Date:  2011-07-18       Impact factor: 5.191

7.  Species Distribution and Comparison between EUCAST and Gradient Concentration Strips Methods for Antifungal Susceptibility Testing of 112 Aspergillus Section Nigri Isolates.

Authors:  B Carrara; R Richards; S Imbert; F Morio; M Sasso; N Zahr; A C Normand; P Le Pape; L Lachaud; S Ranque; D Maubon; R Piarroux; A Fekkar
Journal:  Antimicrob Agents Chemother       Date:  2020-06-23       Impact factor: 5.191

8.  Pharmacodynamics and dose-response relationships of liposomal amphotericin B against different azole-resistant Aspergillus fumigatus isolates in a murine model of disseminated aspergillosis.

Authors:  Seyedmojtaba Seyedmousavi; Willem J G Melchers; Johan W Mouton; Paul E Verweij
Journal:  Antimicrob Agents Chemother       Date:  2013-02-04       Impact factor: 5.191

9.  Evaluating the resistance to posaconazole by E-test and CLSI broth microdilution methodologies of Candida spp. and pathogenic moulds.

Authors:  R Araujo; S Costa-de-Oliveira; I Coutinho; A G Rodrigues; C Pina-Vaz
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2009-04-07       Impact factor: 3.267

10.  Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus.

Authors:  Fabio Gsaller; Takanori Furukawa; Paul D Carr; Bharat Rash; Christoph Jöchl; Margherita Bertuzzi; Elaine M Bignell; Michael J Bromley
Journal:  Antimicrob Agents Chemother       Date:  2018-05-25       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.