Literature DB >> 15261647

Large-scale analysis of pseudogenes in the human genome.

ZhaoLei Zhang1, Mark Gerstein.   

Abstract

Pseudogenes are considered as genomic fossils: disabled copies of functional genes that were once active in the ancient genome. Recently, whole-genome computational approaches have revealed thousands of pseudogenes in the genomes of the human and other eukaryotes. Identification of these pseudogenes can improve the accuracy of gene annotation. It also offers new insight on the evolutionary history and the stability of the genome as a whole. Copyright 2004 Elsevier Ltd.

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Year:  2004        PMID: 15261647     DOI: 10.1016/j.gde.2004.06.003

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN: 0959-437X            Impact factor:   5.578


  68 in total

1.  Pseudogenes of rat VDAC1: 16 gene segments in the rat genome show structural similarities with the cDNA encoding rat VDAC1, with 8 slightly expressed in certain tissues.

Authors:  Yusuke Ido; Takenori Yamamoto; Tatsuki Yoshitomi; Atsushi Yamamoto; Eriko Obana; Kazuto Ohkura; Yasuo Shinohara
Journal:  Mamm Genome       Date:  2011-11-20       Impact factor: 2.957

2.  Pseudogene: lessons from PCR bias, identification and resurrection.

Authors:  Shan-Min Chen; Ka-Yan Ma; Jin Zeng
Journal:  Mol Biol Rep       Date:  2010-11-30       Impact factor: 2.316

3.  Iterative gene prediction and pseudogene removal improves genome annotation.

Authors:  Marijke J van Baren; Michael R Brent
Journal:  Genome Res       Date:  2006-05       Impact factor: 9.043

Review 4.  Use it or lose it: molecular evolution of sensory signaling in primates.

Authors:  Emily R Liman
Journal:  Pflugers Arch       Date:  2006-08-03       Impact factor: 3.657

5.  Helitron mediated amplification of cytochrome P450 monooxygenase gene in maize.

Authors:  Natalie Jameson; Nikolaos Georgelis; Eric Fouladbash; Sara Martens; L Curtis Hannah; Shailesh Lal
Journal:  Plant Mol Biol       Date:  2008-06       Impact factor: 4.076

6.  Pseudogenes in the ENCODE regions: consensus annotation, analysis of transcription, and evolution.

Authors:  Deyou Zheng; Adam Frankish; Robert Baertsch; Philipp Kapranov; Alexandre Reymond; Siew Woh Choo; Yontao Lu; France Denoeud; Stylianos E Antonarakis; Michael Snyder; Yijun Ruan; Chia-Lin Wei; Thomas R Gingeras; Roderic Guigó; Jennifer Harrow; Mark B Gerstein
Journal:  Genome Res       Date:  2007-06       Impact factor: 9.043

7.  NDUFV2 pseudogene (NDUFV2P1) contributes to mitochondrial complex I deficits in schizophrenia.

Authors:  Oded Bergman; Rachel Karry; Jumana Milhem; Dorit Ben-Shachar
Journal:  Mol Psychiatry       Date:  2018-12-10       Impact factor: 15.992

8.  Origin and evolution of processed pseudogenes that stabilize functional Makorin1 mRNAs in mice, primates and other mammals.

Authors:  Satoko Kaneko; Ikuko Aki; Kaoru Tsuda; Kazuyuki Mekada; Kazuo Moriwaki; Naoyuki Takahata; Yoko Satta
Journal:  Genetics       Date:  2006-01-16       Impact factor: 4.562

9.  VEGFR-1 Pseudogene Expression and Regulatory Function in Human Colorectal Cancer Cells.

Authors:  Xiangcang Ye; Fan Fan; Rajat Bhattacharya; Seth Bellister; Delphine R Boulbes; Rui Wang; Ling Xia; Cristina Ivan; Xiaofeng Zheng; George A Calin; Jing Wang; Xiongbin Lu; Lee M Ellis
Journal:  Mol Cancer Res       Date:  2015-06-03       Impact factor: 5.852

10.  Little ROCK is a ROCK1 pseudogene expressed in human smooth muscle cells.

Authors:  Maria Claudia Montefusco; Kristen Merlo; Crystal D Bryan; Howard K Surks; Steven E Reis; Michael E Mendelsohn; Gordon S Huggins
Journal:  BMC Genet       Date:  2010-04-14       Impact factor: 2.797

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