Literature DB >> 15255745

A novel route to imidoylbenzotriazoles and their application for the synthesis of enaminones.

Alan R Katritzky1, Amy E Hayden, Kostyantyn Kirichenko, Phillip Pelphrey, Yu Ji.   

Abstract

Reactions of secondary amides 2a-i with 1-chloro-1H-benzotriazole and triphenylphosphine give imidoylbenzotriazoles 3a-i. The treatment of 3a,b,e,g with silyl enol ethers 5a,b in the presence of potassium tert-butoxide provides a new general approach to enaminoketones 6a-h.

Entities:  

Year:  2004        PMID： 15255745     DOI： 10.1021/jo0496594

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

1.  New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer.

Authors:  Giuseppe La Regina; Ruoli Bai; Antonio Coluccia; Valeria Famiglini; Sveva Pelliccia; Sara Passacantilli; Carmela Mazzoccoli; Vitalba Ruggieri; Annalisa Verrico; Andrea Miele; Ludovica Monti; Marianna Nalli; Romina Alfonsi; Lucia Di Marcotullio; Alberto Gulino; Biancamaria Ricci; Alessandra Soriani; Angela Santoni; Michele Caraglia; Stefania Porto; Eleonora Da Pozzo; Claudia Martini; Andrea Brancale; Luciana Marinelli; Ettore Novellino; Stefania Vultaggio; Mario Varasi; Ciro Mercurio; Chiara Bigogno; Giulio Dondio; Ernest Hamel; Patrizia Lavia; Romano Silvestri
Journal:  J Med Chem       Date:  2015-07-20       Impact factor: 7.446

2.  Efficient synthesis of functionalized spiro[indoline-3,4'-pyrrolo[3,4-b]pyridines] via one-pot three-component reaction.

Authors:  Chao Wang; Yan-Hong Jiang; Chao-Guo Yan
Journal:  Mol Divers       Date:  2014-07-31       Impact factor: 2.943

3.  (2Z,2'Z)-Diethyl 3,3'-[butane-1,4-diylbis(aza-nedi-yl)]bis-(but-2-enoate).

Authors:  Mohamed Anouar Harrad; Brahim Boualy; Mustapha Ait Ali; Larbi El Firdoussi; Helen Stoeckli-Evans
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-09-05

4.  Synthesis of functionalized spiro[indoline-3,4'-pyridines] and spiro[indoline-3,4'-pyridinones] via one-pot four-component reactions.

Authors:  Li-Juan Zhang; Qun Wu; Jing Sun; Chao-Guo Yan
Journal:  Beilstein J Org Chem       Date:  2013-05-02       Impact factor: 2.883

5.  Copper-mediated synthesis of N-alkenyl-α,β-unsaturated nitrones and their conversion to tri- and tetrasubstituted pyridines.

Authors:  Dimitra Kontokosta; Daniel S Mueller; Dong-Liang Mo; Wiktoria H Pace; Rachel A Simpson; Laura L Anderson
Journal:  Beilstein J Org Chem       Date:  2015-11-04       Impact factor: 2.883
  5 in total

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