OBJECTIVE: Improvements in survival after childhood cancer have increased emphasis on health-related quality of life (HRQoL) of survivors. We developed the Minneapolis-Manchester Quality of Life-Youth Form (MMQL-YF) as a standardized patient self-report instrument designed to assess HRQoL in childhood cancer survivors between the ages of 8 and 12 years. STUDY DESIGN: To validate the instrument, the MMQL-YF was administered to 643 children (481 healthy, 162 with cancer). Factor analysis was conducted to refine the instrument, and Cronbach's alpha coefficient was used to measure its internal reliability. Known-groups validity was determined by comparing healthy children with those with cancer. Construct validity was studied by a comparison of similar domains in the MMQL-YF and the Child Health Questionnaire (CHQ). Stability was tested by re-administration of the MMQL-YF 2 weeks later. RESULTS: Internal consistency reliability was in the acceptable range for this instrument. The MMQL-YF was able to distinguish between known groups, and its scales correlated highly with similar CHQ domains. Test-retest reliability showed that the instrument was extremely stable in all scales tested. CONCLUSION: Data provide evidence for the validity and reliability of the MMQL-YF as a comprehensive, multidimensional, self-report instrument for measuring HRQoL among childhood cancer survivors.
OBJECTIVE: Improvements in survival after childhood cancer have increased emphasis on health-related quality of life (HRQoL) of survivors. We developed the Minneapolis-Manchester Quality of Life-Youth Form (MMQL-YF) as a standardized patient self-report instrument designed to assess HRQoL in childhood cancer survivors between the ages of 8 and 12 years. STUDY DESIGN: To validate the instrument, the MMQL-YF was administered to 643 children (481 healthy, 162 with cancer). Factor analysis was conducted to refine the instrument, and Cronbach's alpha coefficient was used to measure its internal reliability. Known-groups validity was determined by comparing healthy children with those with cancer. Construct validity was studied by a comparison of similar domains in the MMQL-YF and the Child Health Questionnaire (CHQ). Stability was tested by re-administration of the MMQL-YF 2 weeks later. RESULTS: Internal consistency reliability was in the acceptable range for this instrument. The MMQL-YF was able to distinguish between known groups, and its scales correlated highly with similar CHQ domains. Test-retest reliability showed that the instrument was extremely stable in all scales tested. CONCLUSION: Data provide evidence for the validity and reliability of the MMQL-YF as a comprehensive, multidimensional, self-report instrument for measuring HRQoL among childhood cancer survivors.
Authors: Alysia Bosworth; Elizabeth L Goodman; Eric Wu; Liton Francisco; Leslie L Robison; Smita Bhatia Journal: Qual Life Res Date: 2017-08-02 Impact factor: 4.147
Authors: S K Parsons; M C Shih; D K Mayer; S E Barlow; S E Supran; S L Levy; S Greenfield; S H Kaplan Journal: Qual Life Res Date: 2005-08 Impact factor: 4.147
Authors: Ashley Wilder Smith; Keith M Bellizzi; Theresa H M Keegan; Brad Zebrack; Vivien W Chen; Anne Victoria Neale; Ann S Hamilton; Margarett Shnorhavorian; Charles F Lynch Journal: J Clin Oncol Date: 2013-05-06 Impact factor: 44.544
Authors: Anne F Klassen; Samantha J Anthony; Aalia Khan; Lillian Sung; Robert Klaassen Journal: Support Care Cancer Date: 2011-05-25 Impact factor: 3.603
Authors: John M Salsman; Suzanne C Danhauer; Justin B Moore; Mollie R Canzona; David E Victorson; Bradley J Zebrack; Bryce B Reeve Journal: Cancer Date: 2020-09-10 Impact factor: 6.860
Authors: Laura C Pinheiro; Molly McFatrich; Nicole Lucas; Jennifer S Walker; Janice S Withycombe; Pamela S Hinds; Lillian Sung; Deborah Tomlinson; David R Freyer; Jennifer W Mack; Justin N Baker; Bryce B Reeve Journal: Qual Life Res Date: 2017-09-06 Impact factor: 4.147
Authors: Brad J Zebrack; Janet E Donohue; James G Gurney; Mark A Chesler; Smita Bhatia; Wendy Landier Journal: Qual Life Res Date: 2010-03 Impact factor: 4.147