Literature DB >> 15221360

MACE or caecostomy button for idiopathic constipation in children: a comparison of complications and outcomes.

S Cascio1, M E Flett, M De la Hunt, A M Barrett, B Jaffray.   

Abstract

The Malone antegrade enema (MACE) and the caecostomy button (CB) are two methods of achieving colonic lavage in constipated children with faecal soiling. We reviewed our experience with the MACE and CB, aiming to compare results, complications, and outcomes. Between June 1998 and August 2002, 37 children (15 boys) underwent MACE and 12 children (9 boys) underwent CB for idiopathic constipation that had failed conventional treatment. Rectal biopsy was ganglionic in all cases. Mean age at surgery was 9.9 years for the MACE patients and 9.8 years for the CB patients. All children are under continuous review, and mean follow-up is 18 months. Statistical analysis of proportions used Fisher's exact test. Soiling stopped completely in 30 children with MACE and in 9 with CB. Occasional soiling is still present in two children with a CB and in one with MACE. One child with a CB had resumed regular bowel activity, and the CB was removed. MACE failed in 5 (14%) patients because of ineffective colonic lavage, and in one patient (3%) the appendix was replaced by a CB because of perforation of the appendicostomy. CB failed in one patient (8%) because of faecal leak around the button; the child was subsequently converted to MACE (P = >0.5). Complications requiring operative intervention were seen in 9 (24%) of the 37 patients who underwent MACE and none of the 12 patients who underwent CB (P = 0.09). The main complication requiring surgical intervention was stoma stenosis (11%). Complications not requiring operative intervention were seen in 7 (19%) patients after MACE and 11 (92%) of the 12 patients who underwent CB (P < 0.001). The MACE and CB procedures are reliable and effective with high success rates. The MACE has a higher incidence of complications requiring operative intervention. Conversely, complications not requiring operative intervention are more frequent with CB. CB is a safe and effective alternative to MACE in children with faecal soiling.

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Year:  2004        PMID: 15221360     DOI: 10.1007/s00383-004-1220-9

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  13 in total

1.  Preliminary report: the antegrade continence enema.

Authors:  P S Malone; P G Ransley; E M Kiely
Journal:  Lancet       Date:  1990-11-17       Impact factor: 79.321

Review 2.  The antegrade continence enema procedure: a review of the literature.

Authors:  J L Graf; C Strear; B Bratton; H T Housley; R W Jennings; M R Harrison; C T Albanese
Journal:  J Pediatr Surg       Date:  1998-08       Impact factor: 2.545

3.  Antegrade continence enemas in the treatment of slow-transit constipation.

Authors:  J Marshall; J M Hutson; N Anticich; M P Stanton
Journal:  J Pediatr Surg       Date:  2001-08       Impact factor: 2.545

4.  The MACE procedure: experience in the United Kingdom.

Authors:  J I Curry; A Osborne; P S Malone
Journal:  J Pediatr Surg       Date:  1999-02       Impact factor: 2.545

5.  How to achieve a successful Malone antegrade continence enema.

Authors:  J I Curry; A Osborne; P S Malone
Journal:  J Pediatr Surg       Date:  1998-01       Impact factor: 2.545

6.  Clinical approach to fecal soiling in children.

Authors:  V Loening-Baucke
Journal:  Clin Pediatr (Phila)       Date:  2000-10       Impact factor: 1.168

7.  Comparison of results of laparoscopic and open antegrade continence enema procedures.

Authors:  A C Lynch; S W Beasley; R W Robertson; P N Morreau
Journal:  Pediatr Surg Int       Date:  1999-07       Impact factor: 1.827

Review 8.  The physiology of continence: idiopathic fecal constipation and soiling.

Authors:  D M Griffiths
Journal:  Semin Pediatr Surg       Date:  2002-05       Impact factor: 2.754

9.  Factors that influence outcomes of the Mitrofanoff and Malone antegrade continence enema reconstructive procedures in children.

Authors:  Travis Clark; John C Pope; mark C Adams; Nancy Wells; John W Brock
Journal:  J Urol       Date:  2002-10       Impact factor: 7.450

10.  The Malone antegrade colonic enema enhances the quality of life in children undergoing urological incontinence procedures.

Authors:  P I Ellsworth; H W Webb; J M Crump; M A Barraza; P S Stevens; H G Mesrobian
Journal:  J Urol       Date:  1996-04       Impact factor: 7.450

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  12 in total

1.  Antegrade continence enema (ACE): current practice.

Authors:  Chandrasen Kumar Sinha; Alka Grewal; Harry C Ward
Journal:  Pediatr Surg Int       Date:  2008-04-12       Impact factor: 1.827

2.  Cecostomy in children with defecation disorders.

Authors:  Hayat M Mousa; Maartje M van den Berg; Donna A Caniano; Mark Hogan; Carlo Di Lorenzo; John Hayes
Journal:  Dig Dis Sci       Date:  2006-01       Impact factor: 3.199

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Journal:  J Neurogastroenterol Motil       Date:  2011-01-26       Impact factor: 4.924

Review 4.  Malone Antegrade Continence Enemas vs. Cecostomy vs. Transanal Irrigation-What Is New and How Do We Counsel Our Patients?

Authors:  Maryellen S Kelly
Journal:  Curr Urol Rep       Date:  2019-06-10       Impact factor: 3.092

Review 5.  Constipation in childhood.

Authors:  Suzanne M Mugie; Carlo Di Lorenzo; Marc A Benninga
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2011-08-02       Impact factor: 46.802

6.  Gastrointestinal motility disorders in children.

Authors:  Lusine Ambartsumyan; Leonel Rodriguez
Journal:  Gastroenterol Hepatol (N Y)       Date:  2014-01

7.  Long-term follow-up of patients after antegrade continence enema procedure.

Authors:  Anees A Siddiqui; Steven J Fishman; Stuart B Bauer; Samuel Nurko
Journal:  J Pediatr Gastroenterol Nutr       Date:  2011-05       Impact factor: 2.839

8.  The success rate of antegrade enemas for the management of idiopathic constipation.

Authors:  Marina L Reppucci; Margo M Nolan; Emily Cooper; Lea A Wehrli; Julie Schletker; Jill Ketzer; Alberto Peña; Andrea Bischoff; Luis De la Torre
Journal:  Pediatr Surg Int       Date:  2022-09-15       Impact factor: 2.003

Review 9.  Surgical Management of Idiopathic Constipation in Pediatric Patients.

Authors:  Lily S Cheng; Allan M Goldstein
Journal:  Clin Colon Rectal Surg       Date:  2018-02-25

Review 10.  Novel and alternative therapies for childhood constipation.

Authors:  Olivia Liem; Marc A Benninga; Hayat M Mousa; Carlo Di Lorenzo
Journal:  Curr Gastroenterol Rep       Date:  2007-06
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