Literature DB >> 15215283

The estimation of relative fitness and frailty in community-dwelling older adults using self-report data.

Arnold B Mitnitski1, Xiaowei Song, Kenneth Rockwood.   

Abstract

BACKGROUND: While on average health declines with age, it also becomes more variable with age. As a consequence of this marked variability, it becomes more important as people age to have a means of summarizing health status, but how precisely to do so remains controversial. We developed one measure of health status, personal biological age, from a frailty index. The index itself is a count of deficits derived, in the first instance, from a clinical database. In our earlier investigations, personal biological age demonstrated a strong relationship with 6-year survival. Here we extend this approach to self-reported data.
METHODS: This is a secondary analysis of community-dwelling people aged 65 years and older (n = 9008) in the Canadian Study of Health and Aging. The frailty index was calculated from 40 self-reported variables, representing symptoms, attitudes, illnesses, and function. Personal biological age was estimated for each individual as the age corresponding to the mean chronological age for the index value. Individual frailty (and the related construct of fitness) was calculated as the difference between chronological and personal biological age.
RESULTS: The frailty index showed, on average, an exponential increase with age at an average rate of 3% per year. Although women, on average, demonstrate more frailty than men of the same chronological age, their survival chances are greater. The frailty index strongly correlated (Pearson r =.992 for women and.955 for men) with survival.
CONCLUSIONS: A frailty index, based on self-report data, can be used as a tool for capturing heterogeneity in the health status of older adults.

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Mesh:

Year:  2004        PMID: 15215283     DOI: 10.1093/gerona/59.6.m627

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN: 1079-5006            Impact factor:   6.053


  66 in total

1.  Frailty and Mortality Outcomes in Cognitively Normal Older People: Sex Differences in a Population-Based Study.

Authors:  Mairead M Bartley; Yonas E Geda; Teresa J H Christianson; V Shane Pankratz; Rosebud O Roberts; Ronald C Petersen
Journal:  J Am Geriatr Soc       Date:  2016-01       Impact factor: 5.562

2.  Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data.

Authors:  Alexander Kulminski; Anatoli Yashin; Svetlana Ukraintseva; Igor Akushevich; Konstantin Arbeev; Kenneth Land; Kenneth Manton
Journal:  Mech Ageing Dev       Date:  2006-09-14       Impact factor: 5.432

3.  Cumulative index of health disorders as an indicator of aging-associated processes in the elderly: results from analyses of the National Long Term Care Survey.

Authors:  A Kulminski; A Yashin; K Arbeev; I Akushevich; S Ukraintseva; K Land; K Manton
Journal:  Mech Ageing Dev       Date:  2006-12-20       Impact factor: 5.432

4.  Accelerated accumulation of health deficits as a characteristic of aging.

Authors:  Alexander Kulminski; Svetlana V Ukraintseva; Igor Akushevich; Konstantin G Arbeev; Kenneth Land; Anatoli I Yashin
Journal:  Exp Gerontol       Date:  2007-05-29       Impact factor: 4.032

5.  Frailty: an emerging research and clinical paradigm--issues and controversies.

Authors:  Howard Bergman; Luigi Ferrucci; Jack Guralnik; David B Hogan; Silvia Hummel; Sathya Karunananthan; Christina Wolfson
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2007-07       Impact factor: 6.053

6.  What age trajectories of cumulative deficits and medical costs tell us about individual aging and mortality risk: Findings from the NLTCS-Medicare data.

Authors:  Anatoli I Yashin; Konstantin G Arbeev; Alexander Kulminski; Igor Akushevich; Lucy Akushevich; Svetlana V Ukraintseva
Journal:  Mech Ageing Dev       Date:  2008-02-01       Impact factor: 5.432

7.  Prevalence of aging population in the Middle East and its implications on cancer incidence and care.

Authors:  R R Hajjar; T Atli; Z Al-Mandhari; M Oudrhiri; L Balducci; M Silbermann
Journal:  Ann Oncol       Date:  2013-10       Impact factor: 32.976

8.  Prediction of severe, persistent activity-of-daily-living disability in older adults.

Authors:  Dae Hyun Kim; Anne B Newman; Lewis A Lipsitz
Journal:  Am J Epidemiol       Date:  2013-06-19       Impact factor: 4.897

9.  Relationship between persistent pain and 5-year mortality: a population-based prospective cohort study.

Authors:  Joseph W Shega; Melissa Andrew; Ashwin Kotwal; Denys T Lau; Keela Herr; Mary Ersek; Debra K Weiner; Marshall H Chin; William Dale
Journal:  J Am Geriatr Soc       Date:  2013-12-09       Impact factor: 5.562

10.  Self-reported frailty is associated with low calcaneal bone mineral density in a multiracial population of community-dwelling elderly.

Authors:  S-L Ma; J Oyler; S Glavin; A Alavi; T Vokes
Journal:  Osteoporos Int       Date:  2009-03-18       Impact factor: 4.507

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