| Literature DB >> 15188144 |
Sarah J Nyante1, Sandy Devries, Yunn Yi Chen, E Shelley Hwang.
Abstract
It has been increasingly recognized that ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive cancer of the breast are often closely associated with one another. However, the genomic relationship between these histologically distinct entities has not been well characterized. Refinements in high-resolution comparative genomic hybridization (CGH) techniques allow for a detailed comparison of genomic alterations in synchronously occurring tumors. The following case illustrates how array CGH may be used to better understand whether synchronous neoplasms share a common origin.Entities:
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Year: 2004 PMID： 15188144 DOI： 10.1016/j.humpath.2003.11.009
Source DB: PubMed Journal: Hum Pathol ISSN： 0046-8177 Impact factor: 3.466