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Literature DB >> 15184477

Survey of ferroxidase expression and siderophore production in clinical isolates of Pseudomonas aeruginosa.

Wilhelmina M Huston¹, Adam J Potter, Michael P Jennings, Jordi Rello, Alan R Hauser, Alastair G McEwan.

Abstract

Ferroxidase (encoded by the mco gene), a component of a ferrous iron uptake pathway in Pseudomonas aeruginosa, was detected in all of the 35 respiratory clinical isolates surveyed; in contrast, considerable variation in siderophore expression was observed. The ubiquitous expression of this periplasmic ferroxidase suggests that it plays a key role in iron uptake in this opportunistic pathogen.

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Year: 2004 PMID： 15184477 PMCID： PMC427835 DOI： 10.1128/JCM.42.6.2806-2809.2004

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

21 in total

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