| Literature DB >> 1515034 |
C Y Wu1, S T Chen, S H Chiou, K T Wang.
Abstract
A rapid and selective peptide-bond cleavage in weak acid, induced by microwave irradiation, has been developed. The specific cleavage sites of peptide bonds located only at the carboxyl- and amino-terminal ends of aspartyl residues along the peptide chain. A systematic study including the time course for the cleavage of various aspartyl-containing peptides, the effect of the acidity of the reaction solution on the completeness of peptide-bond cleavage, and the relationship between the power of microwave irradiation and the reaction time of cleavage are studied.Mesh：
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Year: 1992 PMID： 1515034 DOI： 10.1007/bf01025091
Source DB: PubMed Journal: J Protein Chem ISSN： 0277-8033