| Literature DB >> 15137741 |
Yamuna Krishnan-Ghosh1, Elaine Stephens, Shankar Balasubramanian.
Abstract
A tetrameric PNA, TGGG, has been shown to form an intermolecular G-quadruplex. Nanoelectrospray mass spectrometry, combined with solution-phase H/D exchange, established formation of a specific tetramolecular complex. UV melting studies show that this complex undergoes a quadruplex melting transition. This is a novel four-stranded structure that offers the gross structural features of a DNA quadruplex, but without the negatively charged backbone.Mesh：
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Year: 2004 PMID： 15137741 DOI： 10.1021/ja031508f
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419