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Literature DB >> 20177616

Programing the formation of DNA and PNA quadruplexes by pi-pi-stacking interactions.

Sourav Saha¹, Jianfeng Cai, Daniel Eiler, Andrew D Hamilton.

Abstract

Guanine (G) rich G(4)T(4)G(4) DNA and homologous PNA strands tend to form antiparallel dimeric quadruplexes. In contrast, the same DNA strands carrying planar aromatic 5'-residues preferentially form parallel DNA quadruplex. Conformation and composition of the DNA quadruplexes can be programed by pi-pi-stacking interaction exerted by the 5'-residues.

Entities: Chemical Species

Mesh：

Substances：
Peptide Nucleic Acids
DNA

Year: 2010 PMID： 20177616 PMCID： PMC3186060 DOI： 10.1039/b915955j

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

11 in total

1. Hybridization of PNA to structured DNA targets: quadruplex invasion and the overhang effect.

Authors: B Datta; B A Armitage
Journal: J Am Chem Soc Date: 2001-10-03 Impact factor: 15.419

2. Formation of a PNA2-DNA2 hybrid quadruplex.

Authors: Bhaskar Datta; Christoph Schmitt; Bruce A Armitage
Journal: J Am Chem Soc Date: 2003-04-09 Impact factor: 15.419

3. Structural transition from antiparallel to parallel G-quadruplex of d(G4T4G4) induced by Ca2+.

Authors: Daisuke Miyoshi; Akihiro Nakao; Naoki Sugimoto
Journal: Nucleic Acids Res Date: 2003-02-15 Impact factor: 16.971

4. A PNA4 quadruplex.

Authors: Yamuna Krishnan-Ghosh; Elaine Stephens; Shankar Balasubramanian
Journal: J Am Chem Soc Date: 2004-05-19 Impact factor: 15.419

5. Protein recognition and denaturation by self-assembling fragments on a DNA quadruplex scaffold.

Authors: Debarati M Tagore; K Ingrid Sprinz; Steven Fletcher; Janarthanan Jayawickramarajah; Andrew D Hamilton
Journal: Angew Chem Int Ed Engl Date: 2007 Impact factor: 15.336

6. Allosteric control of self-assembly: modulating the formation of guanine quadruplexes through orthogonal aromatic interactions.

Authors: Janarthanan Jayawickramarajah; Debarati M Tagore; Lun K Tsou; Andrew D Hamilton
Journal: Angew Chem Int Ed Engl Date: 2007 Impact factor: 15.336

7. High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element.

Authors: Subhadeep Roy; Farial A Tanious; W David Wilson; Danith H Ly; Bruce A Armitage
Journal: Biochemistry Date: 2007-08-24 Impact factor: 3.162

Programing the formation of DNA and PNA quadruplexes by pi-pi-stacking interactions.

1. Hybridization of PNA to structured DNA targets: quadruplex invasion and the overhang effect.

2. Formation of a PNA2-DNA2 hybrid quadruplex.

3. Structural transition from antiparallel to parallel G-quadruplex of d(G4T4G4) induced by Ca2+.

4. A PNA4 quadruplex.

5. Protein recognition and denaturation by self-assembling fragments on a DNA quadruplex scaffold.

6. Allosteric control of self-assembly: modulating the formation of guanine quadruplexes through orthogonal aromatic interactions.

7. High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element.

8. Redesigned tetrads with altered hydrogen bonding patterns enable programming of quadruplex topologies.

Review 9. Peptide nucleic acids (PNA): synthesis, properties and potential applications.

10. Quadruplex formation by a guanine-rich PNA oligomer.

Review 1. Nanoarchitectonics with Porphyrin Functionalized DNA.