Literature DB >> 15134478

Predicting subjective judgment of best focus with objective image quality metrics.

Xu Cheng1, Arthur Bradley, Larry N Thibos.   

Abstract

PURPOSE: To determine the impact of higher-order monochromatic aberrations on lower-order subjective sphero-cylindrical refractions.
METHODS: Computationally-aberrated, monochromatic Sloan letters were presented on a high luminance display that was viewed by an observer through a 2.5mm pupil. Through-focus visual acuity (VA) was determined in the presence of spherical aberration (Z40) at three levels (0.10, 0.21 and 0.50D). Analogous through-astigmatism experiments measured visual acuity in the presence of secondary astigmatism (Z4+/-2) or coma (Z3-1). Measured visual acuity was correlated with 31 different metrics of image quality to determine which metric best predicts performance for degraded retinal images. The defocus and astigmatism levels that optimized each metric were compared with those that produced best visual acuity to determine which metric best predicts subjective refraction.
RESULTS: Spherical aberration, coma and secondary astigmatism all reduced VA and increased depth of focus. The levels of defocus and primary astigmatism that produced the best performance varied with levels of spherical aberration and secondary astigmatism, respectively. The presence of coma, however, did not affect cylindrical refraction. Image plane metrics, especially those that take into account the neural contrast sensitivity threshold (e.g. the visual Strehl ratio, VSOTF), are good predictors of visual acuity in both the through-focus and through-astigmatism experiments (R = -0.822 for VSOTF). Subjective sphero-cylindrical refractions were accurately predicted by some image-quality metrics (e.g., pupil fraction, VSOTF and standard deviation of PSF light distribution).
CONCLUSION: Subjective judgment of best focus does not minimize RMS wavefront error (Zernike defocus = 0), nor create paraxial focus (Seidel defocus = 0), but makes the retina conjugate to a plane between these two. It is possible to precisely predict subjective sphero-cylindrical refraction for monochromatic light using objective metrics.

Entities:  

Mesh:

Year:  2004        PMID: 15134478     DOI: 10.1167/4.4.7

Source DB:  PubMed          Journal:  J Vis        ISSN: 1534-7362            Impact factor:   2.240


  60 in total

1.  Monochromatic ocular wave aberrations in young monkeys.

Authors:  Ramkumar Ramamirtham; Chea-su Kee; Li-Fang Hung; Ying Qiao-Grider; Austin Roorda; Earl L Smith
Journal:  Vision Res       Date:  2006-06-05       Impact factor: 1.886

2.  The effect of optical zone decentration on lower- and higher-order aberrations after photorefractive keratectomy in a cat model.

Authors:  Jens Bühren; Geunyoung Yoon; Shawn Kenner; Scott MacRae; Krystel Huxlin
Journal:  Invest Ophthalmol Vis Sci       Date:  2007-12       Impact factor: 4.799

Review 3.  [Application of wavefront analysis in clinical and scientific settings. From irregular astigmatism to aberrations of a higher order--Part II: examples].

Authors:  J Bühren; T Kohnen
Journal:  Ophthalmologe       Date:  2007-11       Impact factor: 1.059

4.  [Application of wavefront analysis in clinical and scientific settings. From irregular astigmatism to aberrations of a higher order--Part I: Basic principles].

Authors:  J Bühren; T Kohnen
Journal:  Ophthalmologe       Date:  2007-10       Impact factor: 1.059

5.  Optical quality of the eye degraded by time-varying wavefront aberrations with tear film dynamics.

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Journal:  Jpn J Ophthalmol       Date:  2007-08-03       Impact factor: 2.447

6.  Accommodation in emmetropic and myopic young adults wearing bifocal soft contact lenses.

Authors:  Janice Tarrant; Holly Severson; Christine F Wildsoet
Journal:  Ophthalmic Physiol Opt       Date:  2008-01       Impact factor: 3.117

7.  Change in visual acuity is well correlated with change in image-quality metrics for both normal and keratoconic wavefront errors.

Authors:  Ayeswarya Ravikumar; Jason D Marsack; Harold E Bedell; Yue Shi; Raymond A Applegate
Journal:  J Vis       Date:  2013-11-26       Impact factor: 2.240

8.  Comparison of spherical aberration and small-pupil profiles in improving depth of focus for presbyopic corrections.

Authors:  Adam Hickenbotham; Pavan Tiruveedhula; Austin Roorda
Journal:  J Cataract Refract Surg       Date:  2012-09-30       Impact factor: 3.351

9.  Normative best-corrected values of the visual image quality metric VSX as a function of age and pupil size.

Authors:  Gareth D Hastings; Jason D Marsack; Larry N Thibos; Raymond A Applegate
Journal:  J Opt Soc Am A Opt Image Sci Vis       Date:  2018-05-01       Impact factor: 2.129

10.  Optical effects of anti-TGFbeta treatment after photorefractive keratectomy in a cat model.

Authors:  Jens Bühren; Lana Nagy; Jennifer N Swanton; Shawn Kenner; Scott MacRae; Richard P Phipps; Krystel R Huxlin
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-10-24       Impact factor: 4.799

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