BACKGROUND: We compared efficacy of and pain felt after biphasic truncated exponential (BTE) and monophasic damped sine (MDS) shocks in patients undergoing external cardioversion of atrial fibrillation (AF). METHODS:Patients with AF were randomized to BTE or MDS waveform cardioversion. Successive shocks were delivered at 70, 100, 200, and 360 J until successful cardioversion, with one 360 J attempt of the alternate waveform when all 4 shocks failed. Success was determined by blinded over-read of electrocardiograms. Peak current was calculated from energy and impedance. Patients rated their pain at 1 and 24 hours after cardioversion. RESULTS: Fourteen of 37 (38%) patients treated with MDS and 34 of 35 (97%) treated with BTE shocks were cardioverted at < or =200 J (P <.0001). Success rates of MDS versus BTE shocks were 5.4% versus 60% for 70 J, 19% versus 80% for < or =100 J, and 86% versus 97% for < or =360 J. BTE shocks cardioverted with less peak current (14.0 +/- 4.3 vs 39.5 +/- 11.2 A, P <.0001), less energy (97 +/- 47 vs 278 +/- 120 J, P <.0001), and less cumulative energy (146 +/- 116 vs 546 +/- 265 J, P <.0001). Patients felt less pain after BTE than MDS shocks at 1 hour (P <.0001) and 24 hours (P <.0001) after cardioversion. CONCLUSION: This BTE waveform is superior to the MDS waveform for cardioversion of AF, requiring much less energy and current, and causing less postprocedural pain.
RCT Entities:
BACKGROUND: We compared efficacy of and pain felt after biphasic truncated exponential (BTE) and monophasic damped sine (MDS) shocks in patients undergoing external cardioversion of atrial fibrillation (AF). METHODS:Patients with AF were randomized to BTE or MDS waveform cardioversion. Successive shocks were delivered at 70, 100, 200, and 360 J until successful cardioversion, with one 360 J attempt of the alternate waveform when all 4 shocks failed. Success was determined by blinded over-read of electrocardiograms. Peak current was calculated from energy and impedance. Patients rated their pain at 1 and 24 hours after cardioversion. RESULTS: Fourteen of 37 (38%) patients treated with MDS and 34 of 35 (97%) treated with BTE shocks were cardioverted at < or =200 J (P <.0001). Success rates of MDS versus BTE shocks were 5.4% versus 60% for 70 J, 19% versus 80% for < or =100 J, and 86% versus 97% for < or =360 J. BTE shocks cardioverted with less peak current (14.0 +/- 4.3 vs 39.5 +/- 11.2 A, P <.0001), less energy (97 +/- 47 vs 278 +/- 120 J, P <.0001), and less cumulative energy (146 +/- 116 vs 546 +/- 265 J, P <.0001). Patients felt less pain after BTE than MDS shocks at 1 hour (P <.0001) and 24 hours (P <.0001) after cardioversion. CONCLUSION: This BTE waveform is superior to the MDS waveform for cardioversion of AF, requiring much less energy and current, and causing less postprocedural pain.
Authors: Flavio H Fenton; Stefan Luther; Elizabeth M Cherry; Niels F Otani; Valentin Krinsky; Alain Pumir; Eberhard Bodenschatz; Robert F Gilmour Journal: Circulation Date: 2009-07-27 Impact factor: 29.690
Authors: Scott R Ceresnak; Thomas J Starc; Allan J Hordof; Robert H Pass; William J Bonney; Leonardo Liberman Journal: Pediatr Cardiol Date: 2009-04-14 Impact factor: 1.655
Authors: Frency Varghese; Johanna U Neuber; Fei Xie; Jonathan M Philpott; Andrei G Pakhomov; Christian W Zemlin Journal: Cardiovasc Res Date: 2017-12-01 Impact factor: 10.787
Authors: Stefan Luther; Flavio H Fenton; Bruce G Kornreich; Amgad Squires; Philip Bittihn; Daniel Hornung; Markus Zabel; James Flanders; Andrea Gladuli; Luis Campoy; Elizabeth M Cherry; Gisa Luther; Gerd Hasenfuss; Valentin I Krinsky; Alain Pumir; Robert F Gilmour; Eberhard Bodenschatz Journal: Nature Date: 2011-07-13 Impact factor: 49.962
Authors: Jasmeet Soar; Bernd W Böttiger; Pierre Carli; Keith Couper; Charles D Deakin; Therese Djärv; Carsten Lott; Theresa Olasveengen; Peter Paal; Tommaso Pellis; Gavin D Perkins; Claudio Sandroni; Jerry P Nolan Journal: Notf Rett Med Date: 2021-06-08 Impact factor: 0.826