| Literature DB >> 15109651 |
Yurngdong Jahng1, Long-Xuan Zhao, Yoon-Soo Moon, Arjun Basnet, Eun-kyung Kim, Hyeun Wook Chang, Hye Kyung Ju, Tae Cheon Jeong, Eung-Seok Lee.
Abstract
For the development of safer anti-inflammatory agents, simple aromatic compounds containing propenone moiety were prepared and evaluated for their dual COX/5-LOX inhibitory activities. Among the 17 prepared compounds, most of the compounds exhibited considerable COX/5-LOX inhibitory activities. Especially compound C(15) showed the most significant dual COX/5-LOX inhibitory activity.Entities:
Mesh：
Substances：
Year: 2004 PMID： 15109651 DOI： 10.1016/j.bmcl.2004.02.099
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823