Literature DB >> 15056964

A new alkaloid and its artificial derivative with an indazole ring from Nigella glandulifera.

Yu-Ming Liu1, Jun-Shan Yang, Qing-Hua Liu.   

Abstract

A new compound, nigeglanine (1), and its new artificial derivative (1a), were isolated from the seeds of Nigella glandulifera, together with a known aporphine alkaloid, fuzitine (2). Their structures were established by spectral analysis, including two-dimensional (2D)-NMR spectroscopy. Nigeglanine (1) is the third natural product determined to contain an indazole nucleus.

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Year:  2004        PMID： 15056964     DOI： 10.1248/cpb.52.454

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  9 in total

1.  Synthesis of fused indazole ring systems and application to nigeglanine hydrobromide.

Authors:  Aaron C Sather; Orion B Berryman; Julius Rebek
Journal:  Org Lett       Date:  2012-03-02       Impact factor: 6.005

2.  Flavonol glycosides, nigelflavonosides A-F from the whole plant of Nigella glandulifera (Ranunculaceae).

Authors:  Yi Zhang; Dandan Ge; Qiu Chen; Wei He; Lifeng Han; Hongyan Wei; Xiaoguang Jia; Tao Wang
Journal:  J Nat Med       Date:  2012-02-12       Impact factor: 2.343

3.  Cancer chemopreventive potential of volatile oil from black cumin seeds, Nigella sativa L., in a rat multi-organ carcinogenesis bioassay.

Authors:  Elsayed I Salim
Journal:  Oncol Lett       Date:  2010-09-01       Impact factor: 2.967

4.  Cytotoxicity of two triterpenoids from Nigella glandulifera.

Authors:  Ze Tian; Yu-Ming Liu; Si-Bao Chen; Jun-Shan Yang; Pei-Gen Xiao; Liao Wang; Erxi Wu
Journal:  Molecules       Date:  2006-09-13       Impact factor: 4.411

5.  Osmium(IV) complexes with 1H- and 2H-indazoles: tautomer identity versus spectroscopic properties and antiproliferative activity.

Authors:  Gabriel E Büchel; Iryna N Stepanenko; Michaela Hejl; Michael A Jakupec; Bernhard K Keppler; Petra Heffeter; Walter Berger; Vladimir B Arion
Journal:  J Inorg Biochem       Date:  2012-04-10       Impact factor: 4.155

6.  Indazole-type alkaloids from Nigella sativa seeds exhibit antihyperglycemic effects via AMPK activation in vitro.

Authors:  Tao Yuan; Pragati Nahar; Meenakshi Sharma; Ke Liu; Angela Slitt; H A Aisa; Navindra P Seeram
Journal:  J Nat Prod       Date:  2014-10-09       Impact factor: 4.050

7.  Suzuki-Type Cross-Coupling Reaction of Unprotected 3-Iodoindazoles with Pinacol Vinyl Boronate: An Expeditive C-3 Vinylation of Indazoles under Microwave Irradiation.

Authors:  Gonzalo Vera; Benjamín Diethelm; Claudio A Terraza; Gonzalo Recabarren-Gajardo
Journal:  Molecules       Date:  2018-08-16       Impact factor: 4.411

8.  An optimized procedure for direct access to 1H-indazole-3-carboxaldehyde derivatives by nitrosation of indoles.

Authors:  Arnaud Chevalier; Abdelaaziz Ouahrouch; Alexandre Arnaud; Thibault Gallavardin; Xavier Franck
Journal:  RSC Adv       Date:  2018-04-09       Impact factor: 3.361

9.  1-(4-Methyl-phenyl-sulfon-yl)-5,6-di-nitro-1H-indazole.

Authors:  Bassou Oulemda; El Mostapha Rakib; Najat Abbassi; Mohamed Saadi; Lahcen El Ammari
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-12-24
  9 in total

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