Literature DB >> 15020450

One-hybrid screens at the Saccharomyces cerevisiae HMR locus identify novel transcriptional silencing factors.

Erik D Andrulis1, David C Zappulla, Krassimira Alexieva-Botcheva, Carlos Evangelista, Rolf Sternglanz.   

Abstract

In Saccharomyces cerevisiae, genes located at the telomeres and the HM loci are subject to transcriptional silencing. Here, we report results of screening a Gal4 DNA-binding domain hybrid library for proteins that cause silencing when targeted to a silencer-defective HMR locus.

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Year:  2004        PMID： 15020450      PMCID： PMC1470702          DOI： 10.1534/genetics.166.1.631

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  24 in total

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Journal:  Cell       Date:  1987-12-04       Impact factor: 41.582

4.  Multiple interactions in Sir protein recruitment by Rap1p at silencers and telomeres in yeast.

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5.  A novel form of transcriptional silencing by Sum1-1 requires Hst1 and the origin recognition complex.

Authors:  A Sutton; R C Heller; J Landry; J S Choy; A Sirko; R Sternglanz
Journal:  Mol Cell Biol       Date:  2001-05       Impact factor: 4.272

6.  Mutations in the HML E silencer of Saccharomyces cerevisiae yield metastable inheritance of transcriptional repression.

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  13 in total

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4.  Esc4/Rtt107 and the control of recombination during replication.

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7.  Saccharomyces cerevisiae Esc2p interacts with Sir2p through a small ubiquitin-like modifier (SUMO)-binding motif and regulates transcriptionally silent chromatin in a locus-dependent manner.

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8.  Conversion of a replication origin to a silencer through a pathway shared by a Forkhead transcription factor and an S phase cyclin.

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10.  A SUMO-like domain protein, Esc2, is required for genome integrity and sister chromatid cohesion in Saccharomyces cerevisiae.

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