Literature DB >> 15009433

CD40 is required for the optimal induction of protective immunity to Mycobacterium avium.

Manuela Flórido1, Ana Sofia Gonçalves, M Salomé Gomes, Rui Appelberg.   

Abstract

C57Bl/6 mice and mice deficient in the CD40 molecule were infected with three strains of Mycobacterium avium. Two of the M. avium strains proliferated more extensively in CD40-deficient (CD40-/-) mice than in control mice. The increased susceptibility to infection of CD40-/- mice was associated with the generation of poorer interleukin-12 (IL-12) p40 and interferon-gamma (IFN-gamma) responses as compared to the controls, suggesting a role for CD40 in the development of protective immunity. In contrast, direct triggering of CD40 on infected macrophages failed to induce any anti-mycobacterial activity in infected macrophages.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15009433      PMCID: PMC1782428          DOI: 10.1111/j.1365-2567.2004.01812.x

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  29 in total

1.  Antigen specificity of T-cell response to Mycobacterium avium infection in mice.

Authors:  T F Pais; J F Cunha; R Appelberg
Journal:  Infect Immun       Date:  2000-08       Impact factor: 3.441

2.  A role for CD40-CD40 ligand interactions in the generation of type 1 cytokine responses in human leprosy.

Authors:  P S Yamauchi; J R Bleharski; K Uyemura; J Kim; P A Sieling; A Miller; H Brightbill; K Schlienger; T H Rea; R L Modlin
Journal:  J Immunol       Date:  2000-08-01       Impact factor: 5.422

3.  CD40/CD40 ligand interactions in the host defense against disseminated Candida albicans infection: the role of macrophage-derived nitric oxide.

Authors:  Mihai G Netea; Jos W M van der Meer; Ineke Verschueren; Bart Jan Kullberg
Journal:  Eur J Immunol       Date:  2002-05       Impact factor: 5.532

4.  Mycobacterium bovis BCG-induced granuloma formation depends on gamma interferon and CD40 ligand but does not require CD28.

Authors:  L H Hogan; W Markofski; A Bock; B Barger; J D Morrissey; M Sandor
Journal:  Infect Immun       Date:  2001-04       Impact factor: 3.441

5.  The CD40/CD40 ligand interaction is required for resistance to toxoplasmic encephalitis.

Authors:  G Reichmann; W Walker; E N Villegas; L Craig; G Cai; J Alexander; C A Hunter
Journal:  Infect Immun       Date:  2000-03       Impact factor: 3.441

6.  Role of CD40 ligand in Mycobacterium avium infection.

Authors:  T Hayashi; S P Rao; P R Meylan; R S Kornbluth; A Catanzaro
Journal:  Infect Immun       Date:  1999-07       Impact factor: 3.441

7.  Depressed CD40 ligand expression contributes to reduced gamma interferon production in human tuberculosis.

Authors:  B Samten; E K Thomas; J Gong; P F Barnes
Journal:  Infect Immun       Date:  2000-05       Impact factor: 3.441

8.  Impaired Th2 development and increased mortality during Schistosoma mansoni infection in the absence of CD40/CD154 interaction.

Authors:  Andrew S MacDonald; Elisabeth A Patton; Anne C La Flamme; Maria I Araujo; Clive R Huxtable; Beverley Bauman; Edward J Pearce
Journal:  J Immunol       Date:  2002-05-01       Impact factor: 5.422

9.  CD40 ligand (CD154) does not contribute to lymphocyte-mediated inhibition of virulent Mycobacterium tuberculosis within human monocytes.

Authors:  Rhonda Larkin; Christopher D Benjamin; Yen-Ming Hsu; Qing Li; Lynn Zukowski; Richard F Silver
Journal:  Infect Immun       Date:  2002-08       Impact factor: 3.441

10.  Hyper-IgM syndrome with systemic tuberculosis.

Authors:  Isao Ito; Tadashi Ishida; Toru Hashimoto; Machiko Arita; Makoto Osawa; Michiaki Mishima; Shigeaki Nonoyama
Journal:  Scand J Infect Dis       Date:  2002
View more
  9 in total

1.  Impaired dendritic-cell function in ectodermal dysplasia with immune deficiency is linked to defective NEMO ubiquitination.

Authors:  Stephane T Temmerman; Chi A Ma; Louis Borges; Marek Kubin; Shuying Liu; Jonathan M J Derry; Ashish Jain
Journal:  Blood       Date:  2006-06-22       Impact factor: 22.113

Review 2.  Pathogenesis of Mycobacterium avium infection: typical responses to an atypical mycobacterium?

Authors:  Rui Appelberg
Journal:  Immunol Res       Date:  2006       Impact factor: 2.829

3.  Dual roles of CD40 on microbial containment and the development of immunopathology in response to persistent fungal infection in the lung.

Authors:  Gwo-Hsiao Chen; John J Osterholzer; Mun Y Choe; Roderick A McDonald; Michal A Olszewski; Gary B Huffnagle; Galen B Toews
Journal:  Am J Pathol       Date:  2010-09-23       Impact factor: 4.307

4.  The death-promoting molecule tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is not required for the development of peripheral lymphopenia or granuloma necrosis during infection with virulent Mycobacterium avium.

Authors:  M Borges; G T Rosa; R Appelberg
Journal:  Clin Exp Immunol       Date:  2011-04-06       Impact factor: 4.330

5.  I/St mice hypersusceptible to Mycobacterium tuberculosis are resistant to M. avium.

Authors:  E V Kondratieva; V V Evstifeev; T K Kondratieva; S N Petrovskaya; A V Pichugin; E I Rubakova; M M Averbakh; A S Apt
Journal:  Infect Immun       Date:  2007-07-30       Impact factor: 3.441

6.  Differential cytokine secretion and early treatment response in patients with pulmonary tuberculosis.

Authors:  J F Djoba Siawaya; N Beyers; P van Helden; G Walzl
Journal:  Clin Exp Immunol       Date:  2009-01-22       Impact factor: 4.330

7.  Pan-genomic analysis of bovine monocyte-derived macrophage gene expression in response to in vitro infection with Mycobacterium avium subspecies paratuberculosis.

Authors:  David E Machugh; Maria Taraktsoglou; Kate E Killick; Nicolas C Nalpas; John A Browne; Stephen DE Park; Karsten Hokamp; Eamonn Gormley; David A Magee
Journal:  Vet Res       Date:  2012-03-28       Impact factor: 3.683

8.  Difference in virulence of Mycobacterium avium isolates sharing indistinguishable DNA fingerprint determined in murine model of lung infection.

Authors:  Eduardo Pinheiro Amaral; Thereza Liberman Kipnis; Eulógio Carlos Queiróz de Carvalho; Wilmar Dias da Silva; Sylvia Cardoso Leão; Elena B Lasunskaia
Journal:  PLoS One       Date:  2011-06-28       Impact factor: 3.240

9.  X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production.

Authors:  Orchidée Filipe-Santos; Jacinta Bustamante; Margje H Haverkamp; Emilie Vinolo; Cheng-Lung Ku; Anne Puel; David M Frucht; Karin Christel; Horst von Bernuth; Emmanuelle Jouanguy; Jacqueline Feinberg; Anne Durandy; Brigitte Senechal; Ariane Chapgier; Guillaume Vogt; Ludovic de Beaucoudrey; Claire Fieschi; Capucine Picard; Meriem Garfa; Jalel Chemli; Mohamed Bejaoui; Maria N Tsolia; Necil Kutukculer; Alessandro Plebani; Luigi Notarangelo; Christine Bodemer; Frédéric Geissmann; Alain Israël; Michel Véron; Maike Knackstedt; Ridha Barbouche; Laurent Abel; Klaus Magdorf; Dominique Gendrel; Fabrice Agou; Steven M Holland; Jean-Laurent Casanova
Journal:  J Exp Med       Date:  2006-07-03       Impact factor: 14.307

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.