| Literature DB >> 12117990 |
Rhonda Larkin1, Christopher D Benjamin, Yen-Ming Hsu, Qing Li, Lynn Zukowski, Richard F Silver.
Abstract
Human monocytes displayed increased expression of CD40 following infection with virulent Mycobacterium tuberculosis. Nevertheless, soluble CD40 ligand (CD40L; also designated CD154) had no effect on the intracellular growth of the organism. Restriction of the intracellular growth of M. tuberculosis by peripheral blood lymphocytes and antigen-specific CD4+ T-cell lines likewise was not reduced by blocking anti-CD40L monoclonal antibody 5c8.Entities:
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Year: 2002 PMID: 12117990 PMCID: PMC128186 DOI: 10.1128/IAI.70.8.4716-4720.2002
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441