Literature DB >> 15000626

Radiation characteristics of helical tomotherapy.

Robert Jeraj1, Thomas R Mackie, John Balog, Gustavo Olivera, Dave Pearson, Jeff Kapatoes, Ken Ruchala, Paul Reckwerdt.   

Abstract

Helical tomotherapy is a dedicated intensity modulated radiation therapy (IMRT) system with on-board imaging capability (MVCT) and therefore differs from conventional treatment units. Different design goals resulted in some distinctive radiation field characteristics. The most significant differences in the design are the lack of flattening filter, increased shielding of the collimators, treatment and imaging operation modes and narrow fan beam delivery. Radiation characteristics of the helical tomotherapy system, sensitivity studies of various incident electron beam parameters and radiation safety analyses are presented here. It was determined that the photon beam energy spectrum of helical tomotherapy is similar to that of more conventional radiation treatment units. The two operational modes of the system result in different nominal energies of the incident electron beam with approximately 6 MeV and 3.5 MeV in the treatment and imaging modes, respectively. The off-axis mean energy dependence is much lower than in conventional radiotherapy units with less than 5% variation across the field, which is the consequence of the absent flattening filter. For the same reason the transverse profile exhibits the characteristic conical shape resulting in a 2-fold increase of the beam intensity in the center. The radiation leakage outside the field was found to be negligible at less than 0.05% because of the increased shielding of the collimators. At this level the in-field scattering is a dominant source of the radiation outside the field and thus a narrow field treatment does not result in the increased leakage. The sensitivity studies showed increased sensitivity on the incident electron position because of the narrow fan beam delivery and high sensitivity on the incident electron energy, as common to other treatment systems. All in all, it was determined that helical tomotherapy is a system with some unique radiation characteristics, which have been to a large extent optimized for intensity modulated delivery.

Mesh:

Year:  2004        PMID: 15000626     DOI: 10.1118/1.1639148

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  36 in total

1.  Feasibility of intrafraction whole-body motion tracking for total marrow irradiation.

Authors:  Manju Sharma; Troy Dos Santos; Nikolaos P Papanikolopoulos; Susanta Kumar Hui
Journal:  J Biomed Opt       Date:  2011-05       Impact factor: 3.170

2.  Dosimetric properties of a flattening filter-free 6-MV photon beam: a Monte Carlo study.

Authors:  Asghar Mesbahi; Parinaz Mehnati; Ahmad Keshtkar; Alireza Farajollahi
Journal:  Radiat Med       Date:  2007-08-27

3.  Multisource modeling of flattening filter free (FFF) beam and the optimization of model parameters.

Authors:  Woong Cho; Kayla N Kielar; Ed Mok; Lei Xing; Jeong-Hoon Park; Won-Gyun Jung; Tae-Suk Suh
Journal:  Med Phys       Date:  2011-04       Impact factor: 4.071

4.  Three-dimensional patient setup errors at different treatment sites measured by the Tomotherapy megavoltage CT.

Authors:  S K Hui; E Lusczek; T DeFor; K Dusenbery; S Levitt
Journal:  Strahlenther Onkol       Date:  2012-03-09       Impact factor: 3.621

5.  Multi-institutional feasibility study of a fast patient localization method in total marrow irradiation with helical tomotherapy: a global health initiative by the international consortium of total marrow irradiation.

Authors:  Yutaka Takahashi; Stefano Vagge; Stefano Agostinelli; Eunyoung Han; Lukasz Matulewicz; Kai Schubert; Ravishankar Chityala; Vaneerat Ratanatharathorn; Koen Tournel; Jose A Penagaricano; Sterzing Florian; Marc-Andre Mahe; Michael R Verneris; Daniel J Weisdorf; Renzo Corvo; Kathryn E Dusenbery; Guy Storme; Susanta K Hui
Journal:  Int J Radiat Oncol Biol Phys       Date:  2014-10-30       Impact factor: 7.038

6.  Can megavoltage computed tomography reduce proton range uncertainties in treatment plans for patients with large metal implants?

Authors:  Wayne D Newhauser; Annelise Giebeler; Katja M Langen; Dragan Mirkovic; Radhe Mohan
Journal:  Phys Med Biol       Date:  2008-04-17       Impact factor: 3.609

Review 7.  A review of dosimetry studies on external-beam radiation treatment with respect to second cancer induction.

Authors:  X George Xu; Bryan Bednarz; Harald Paganetti
Journal:  Phys Med Biol       Date:  2008-06-09       Impact factor: 3.609

Review 8.  Scintillating Nanoparticles as Energy Mediators for Enhanced Photodynamic Therapy.

Authors:  Anyanee Kamkaew; Feng Chen; Yonghua Zhan; Rebecca L Majewski; Weibo Cai
Journal:  ACS Nano       Date:  2016-04-08       Impact factor: 15.881

9.  Fidelity of dose delivery at high dose rate of volumetric modulated arc therapy in a truebeam linac with flattening filter free beams.

Authors:  Georgios Kalantzis; Jianguo Qian; Bin Han; Gary Luxton
Journal:  J Med Phys       Date:  2012-10

10.  Commissioning experience and quality assurance of helical tomotherapy machines.

Authors:  Amarjit Sen; Matthew K West
Journal:  J Med Phys       Date:  2009-10
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