Literature DB >> 21626926

Multisource modeling of flattening filter free (FFF) beam and the optimization of model parameters.

Woong Cho1, Kayla N Kielar, Ed Mok, Lei Xing, Jeong-Hoon Park, Won-Gyun Jung, Tae-Suk Suh.   

Abstract

PURPOSE: With the introduction of flattening filter free (FFF) linear accelerators to radiation oncology, new analytical source models for a FFF beam applicable to current treatment planning systems is needed. In this work, a multisource model for the FFF beam and the optimization of involved model parameters were designed.
METHODS: The model is based on a previous three source model proposed by Yang et al. ["A three-source model for the calculation of head scatter factors," Med. Phys. 29, 2024-2033 (2002)]. An off axis ratio (OAR) of photon fluence was introduced to the primary source term to generate cone shaped profiles. The parameters of the source model were determined from measured head scatter factors using a line search optimization technique. The OAR of the photon fluence was determined from a measured dose profile of a 40 x 40 cm2 field size with the same optimization technique, but a new method to acquire gradient terms for OARs was developed to enhance the speed of the optimization process. The improved model was validated with measured dose profiles from 3 x 3 to 40 x 40 cm2 field sizes at 6 and 10 MV from a TrueBeam STx linear accelerator. Furthermore, planar dose distributions for clinically used radiation fields were also calculated and compared to measurements using a 2D array detector using the gamma index method.
RESULTS: All dose values for the calculated profiles agreed with the measured dose profiles within 0.5% at 6 and 10 MV beams, except for some low dose regions for larger field sizes. A slight overestimation was seen in the lower penumbra region near the field edge for the large field sizes by 1%-4%. The planar dose calculations showed comparable passing rates (> 98%) when the criterion of the gamma index method was selected to be 3%/3 mm.
CONCLUSIONS: The developed source model showed good agreements between measured and calculated dose distributions. The model is easily applicable to any other linear accelerator using FFF beams as the required data include only the measured PDD, dose profiles, and output factors for various field sizes, which are easily acquired during conventional beam commissioning process.

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Year:  2011        PMID: 21626926      PMCID: PMC3188653          DOI: 10.1118/1.3560426

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  28 in total

1.  Head scatter off-axis for megavoltage x rays.

Authors:  Timothy C Zhu; Bengt E Bjärngard
Journal:  Med Phys       Date:  2003-04       Impact factor: 4.071

2.  Radiation characteristics of helical tomotherapy.

Authors:  Robert Jeraj; Thomas R Mackie; John Balog; Gustavo Olivera; Dave Pearson; Jeff Kapatoes; Ken Ruchala; Paul Reckwerdt
Journal:  Med Phys       Date:  2004-02       Impact factor: 4.071

3.  A convolution-superposition dose calculation engine for GPUs.

Authors:  Sami Hissoiny; Benoît Ozell; Philippe Després
Journal:  Med Phys       Date:  2010-03       Impact factor: 4.071

4.  Accurate convolution/superposition for multi-resolution dose calculation using cumulative tabulated kernels.

Authors:  Weiguo Lu; Gustavo H Olivera; Ming-Li Chen; Paul J Reckwerdt; Thomas R Mackie
Journal:  Phys Med Biol       Date:  2005-02-21       Impact factor: 3.609

5.  A flattening filter free photon treatment concept evaluation with Monte Carlo.

Authors:  U Titt; O N Vassiliev; F Pönisch; L Dong; H Liu; R Mohan
Journal:  Med Phys       Date:  2006-06       Impact factor: 4.071

6.  Properties of unflattened photon beams shaped by a multileaf collimator.

Authors:  Falk Pönisch; Uwe Titt; Oleg N Vassiliev; Stephen F Kry; Radhe Mohan
Journal:  Med Phys       Date:  2006-06       Impact factor: 4.071

7.  Semi-empirical procedures for correcting detector size effect on clinical MV x-ray beam profiles.

Authors:  Narayan Sahoo; Abdul M Kazi; Mark Hoffman
Journal:  Med Phys       Date:  2008-11       Impact factor: 4.071

8.  Simulation of large x-ray fields using independently measured source and geometry details.

Authors:  D Sawkey; B A Faddegon
Journal:  Med Phys       Date:  2009-12       Impact factor: 4.071

9.  Extraction of the photon spectra from measured beam parameters.

Authors:  P Bloch; J McDonough
Journal:  Med Phys       Date:  1998-05       Impact factor: 4.071

10.  Generation of photon energy deposition kernels using the EGS Monte Carlo code.

Authors:  T R Mackie; A F Bielajew; D W Rogers; J J Battista
Journal:  Phys Med Biol       Date:  1988-01       Impact factor: 3.609

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  12 in total

1.  Bridging the gap between IMRT and VMAT: dense angularly sampled and sparse intensity modulated radiation therapy.

Authors:  Ruijiang Li; Lei Xing
Journal:  Med Phys       Date:  2011-09       Impact factor: 4.071

2.  Dose verification for respiratory-gated volumetric modulated arc therapy.

Authors:  Jianguo Qian; Lei Xing; Wu Liu; Gary Luxton
Journal:  Phys Med Biol       Date:  2011-07-13       Impact factor: 3.609

3.  An end-to-end examination of geometric accuracy of IGRT using a new digital accelerator equipped with onboard imaging system.

Authors:  Lei Wang; Kayla N Kielar; Ed Mok; Annie Hsu; Sonja Dieterich; Lei Xing
Journal:  Phys Med Biol       Date:  2012-01-18       Impact factor: 3.609

4.  Fidelity of dose delivery at high dose rate of volumetric modulated arc therapy in a truebeam linac with flattening filter free beams.

Authors:  Georgios Kalantzis; Jianguo Qian; Bin Han; Gary Luxton
Journal:  J Med Phys       Date:  2012-10

5.  Equivalent-quality unflattened photon beam modeling, planning, and delivery.

Authors:  Yunfei Huang; Ryan T Flynn; R Alfredo C Siochi; John E Bayouth
Journal:  J Appl Clin Med Phys       Date:  2013-07-08       Impact factor: 2.102

6.  Dosimetric validation of Monaco treatment planning system on an Elekta VersaHD linear accelerator.

Authors:  Ganesh Narayanasamy; Daniel L Saenz; Dewayne Defoor; Niko Papanikolaou; Sotirios Stathakis
Journal:  J Appl Clin Med Phys       Date:  2017-09-25       Impact factor: 2.102

7.  Pinnacle3 modeling and end-to-end dosimetric testing of a Versa HD linear accelerator with the Agility head and flattening filter-free modes.

Authors:  Daniel L Saenz; Ganesh Narayanasamy; Wilbert Cruz; Nikos Papanikolaou; Sotirios Stathakis
Journal:  J Appl Clin Med Phys       Date:  2016-01-08       Impact factor: 2.102

8.  Beam Characterization of 10-MV Photon Beam from Medical Linear Accelerator without Flattening Filter.

Authors:  Tomohiro Shimozato; Yuichi Aoyama; Takuma Matsunaga; Katsuyoshi Tabushi
Journal:  J Med Phys       Date:  2017 Apr-Jun

9.  Commissioning measurements for photon beam data on three TrueBeam linear accelerators, and comparison with Trilogy and Clinac 2100 linear accelerators.

Authors:  Gloria P Beyer
Journal:  J Appl Clin Med Phys       Date:  2013-01-07       Impact factor: 2.102

10.  A Monte Carlo study on electron and neutron contamination caused by the presence of hip prosthesis in photon mode of a 15 MV Siemens PRIMUS linac.

Authors:  Mohammad Taghi Bahreyni Toossi; Marziyeh Behmadi; Mahdi Ghorbani; Hamid Gholamhosseinian
Journal:  J Appl Clin Med Phys       Date:  2013-09-06       Impact factor: 2.102

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