Literature DB >> 14987411

Skin repair and scar formation: the central role of TGF-beta.

Steven R Beanes1, Catherine Dang, Chia Soo, Kang Ting.   

Abstract

Wound healing is a complex process that we have only recently begun to understand. Central to wound repair is transforming growth factor beta (TGF-beta), a cytokine secreted by several different cell types involved in healing. TGF-beta has diverse effects, depending upon the tissue studied. This review focuses on healing in skin, particularly the phases of cutaneous wound repair and the role of TGF-beta in normal and impaired wound-healing models. It also explores TGF-beta activity in scarless foetal wound healing. Knowledge of TGF-beta function in scarless repair is critical to improving healing in clinical scenarios, such as diabetic wounds and hypertrophic scars.

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Year:  2003        PMID: 14987411     DOI: 10.1017/S1462399403005817

Source DB:  PubMed          Journal:  Expert Rev Mol Med        ISSN: 1462-3994            Impact factor:   5.600


  57 in total

Review 1.  MicroRNAs in skin and wound healing.

Authors:  Jaideep Banerjee; Yuk Cheung Chan; Chandan K Sen
Journal:  Physiol Genomics       Date:  2010-10-19       Impact factor: 3.107

Review 2.  Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects.

Authors:  Tianhong Dai; Masamitsu Tanaka; Ying-Ying Huang; Michael R Hamblin
Journal:  Expert Rev Anti Infect Ther       Date:  2011-07       Impact factor: 5.091

Review 3.  Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 2: role of growth factors in normal and pathological wound healing: therapeutic potential and methods of delivery.

Authors:  Tatiana N Demidova-Rice; Michael R Hamblin; Ira M Herman
Journal:  Adv Skin Wound Care       Date:  2012-08       Impact factor: 2.347

Review 4.  New molecular medicine-based scar management strategies.

Authors:  Anna I Arno; Gerd G Gauglitz; Juan P Barret; Marc G Jeschke
Journal:  Burns       Date:  2014-01-15       Impact factor: 2.744

5.  Provisional Matrix Deposition in Hemostasis and Venous Insufficiency: Tissue Preconditioning for Nonhealing Venous Ulcers.

Authors:  Tony J Parker; James A Broadbent; Jacqui A McGovern; Daniel A Broszczak; Christina N Parker; Zee Upton
Journal:  Adv Wound Care (New Rochelle)       Date:  2015-03-01       Impact factor: 4.730

Review 6.  Growth factor delivery strategies for rotator cuff repair and regeneration.

Authors:  Anupama Prabhath; Varadraj N Vernekar; Enid Sanchez; Cato T Laurencin
Journal:  Int J Pharm       Date:  2018-01-06       Impact factor: 5.875

7.  IL-36 Induces Bisphosphonate-Related Osteonecrosis of the Jaw-Like Lesions in Mice by Inhibiting TGF-β-Mediated Collagen Expression.

Authors:  Sol Kim; Drake W Williams; Cindy Lee; Terresa Kim; Atsushi Arai; Songtao Shi; Xinmin Li; Ki-Hyuk Shin; Mo K Kang; No-Hee Park; Reuben H Kim
Journal:  J Bone Miner Res       Date:  2016-10-12       Impact factor: 6.741

8.  Cutaneous scarring: a clinical review.

Authors:  Richard Baker; Fulvio Urso-Baiarda; Claire Linge; Adriaan Grobbelaar
Journal:  Dermatol Res Pract       Date:  2010-02-10

9.  Three-dimensional paper-based model for cardiac ischemia.

Authors:  Bobak Mosadegh; Borna E Dabiri; Matthew R Lockett; Ratmir Derda; Patrick Campbell; Kevin Kit Parker; George M Whitesides
Journal:  Adv Healthc Mater       Date:  2014-02-12       Impact factor: 9.933

Review 10.  MicroRNAs in skin and wound healing.

Authors:  Jaideep Banerjee; Chandan K Sen
Journal:  Methods Mol Biol       Date:  2013
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