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Literature DB >> 20959495

MicroRNAs in skin and wound healing.

Jaideep Banerjee¹, Yuk Cheung Chan, Chandan K Sen.

Abstract

MicroRNAs (miRNAs) are small endogenous RNA molecules ∼22 nt in length. miRNAs are capable of posttranscriptional gene regulation by binding to their target messenger RNAs (mRNAs), leading to mRNA degradation or suppression of translation. miRNAs have recently been shown to play pivotal roles in skin development and are linked to various skin pathologies, cancer, and wound healing. This review focuses on the role of miRNAs in cutaneous biology, the various methods of miRNA modulation, and the therapeutic opportunities in treatment of skin diseases and wound healing.

Entities: Disease

Mesh：

Substances：
MicroRNAs

Year: 2010 PMID： 20959495 PMCID： PMC3110888 DOI： 10.1152/physiolgenomics.00157.2010

Source DB: PubMed Journal: Physiol Genomics ISSN： 1094-8341 Impact factor: 3.107

171 in total

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44 in total

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