| Literature DB >> 14986688 |
Abstract
Cell-cell signalling mediated by the receptor Notch is used widely across the metazoans to determine cell fate and regulate pattern formation. Notch signals via a conserved regulated intramembrane proteolysis. Recent analyses of the cell biology of the Notch receptor have identified several fundamental mechanisms that contribute to regulate Notch signaling activity in space and time.Mesh:
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Year: 2004 PMID: 14986688
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834