Literature DB >> 14982795

Evaluation of acute hematologic and long-term pulmonary toxicities of radioimmunotherapy of Cryptococcus neoformans infection in murine models.

E Dadachova1, R A Bryan, A Frenkel, T Zhang, C Apostolidis, J S Nosanchuk, J D Nosanchuk, A Casadevall.   

Abstract

We evaluated acute hematological and long-term pulmonary toxicity of radioimmunotherapy in murine models of Cryptococcus neoformans infection. Activities up to 250 microCi were well tolerated by healthy A/JCr mice for (213)Bi-18B7 and (188)Re-18B7 monoclonal antibodies. In infected mice, doses up to 150 microCi produced only transient toxicity. The lungs of treated mice had no evidence of radiation fibrosis.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14982795      PMCID： PMC353163          DOI： 10.1128/AAC.48.3.1004-1006.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  8 in total

Review 1.  Review of low-dose-rate radiobiology for clinicians.

Authors:  A D Murtha
Journal:  Semin Radiat Oncol       Date:  2000-04       Impact factor: 5.934

2.  High-linear energy transfer (LET) alpha versus low-LET beta emitters in radioimmunotherapy of solid tumors: therapeutic efficacy and dose-limiting toxicity of 213Bi- versus 90Y-labeled CO17-1A Fab' fragments in a human colonic cancer model.

Authors:  T M Behr; M Béhé; M G Stabin; E Wehrmann; C Apostolidis; R Molinet; F Strutz; A Fayyazi; E Wieland; S Gratz; L Koch; D M Goldenberg; W Becker
Journal:  Cancer Res       Date:  1999-06-01       Impact factor: 12.701

3.  Radiation injury of the lung after three-dimensional conformal radiation therapy.

Authors:  Titus R Koenig; Reginald F Munden; Jeremy J Erasmus; Bradley S Sabloff; Gregory W Gladish; Ritsuko Komaki; Craig W Stevens
Journal:  AJR Am J Roentgenol       Date:  2002-06       Impact factor: 3.959

4.  Selection of radioimmunoconjugates for the therapy of well-established or micrometastatic colon carcinoma.

Authors:  R M Sharkey; R D Blumenthal; T M Behr; G Y Wong; L Haywood; D Forman; G L Griffiths; D M Goldenberg
Journal:  Int J Cancer       Date:  1997-07-29       Impact factor: 7.396

Review 5.  Clinical radioimmunotherapy.

Authors:  S J Knox; R F Meredith
Journal:  Semin Radiat Oncol       Date:  2000-04       Impact factor: 5.934

6.  Ionizing radiation delivered by specific antibody is therapeutic against a fungal infection.

Authors:  Ekaterina Dadachova; Antonio Nakouzi; Ruth A Bryan; Arturo Casadevall
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-20       Impact factor: 11.205

7.  Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B.

Authors:  J Mukherjee; L S Zuckier; M D Scharff; A Casadevall
Journal:  Antimicrob Agents Chemother       Date:  1994-03       Impact factor: 5.191

8.  Susceptibility of the human pathogenic fungi Cryptococcus neoformans and Histoplasma capsulatum to gamma-radiation versus radioimmunotherapy with alpha- and beta-emitting radioisotopes.

Authors:  Ekaterina Dadachova; Roger W Howell; Ruth A Bryan; Annie Frenkel; Joshua D Nosanchuk; Arturo Casadevall
Journal:  J Nucl Med       Date:  2004-02       Impact factor: 10.057
  8 in total
  16 in total

1.  Treatment of early and established Cryptococcus neoformans infection with radiolabeled antibodies in immunocompetent mice.

Authors:  Zewei Jiang; Ruth A Bryan; Alfred Morgenstern; Frank Bruchertseifer; Arturo Casadevall; Ekaterina Dadachova
Journal:  Antimicrob Agents Chemother       Date:  2011-10-17       Impact factor: 5.191

2.  Antibody-guided alpha radiation effectively damages fungal biofilms.

Authors:  L R Martinez; R A Bryan; C Apostolidis; A Morgenstern; A Casadevall; E Dadachova
Journal:  Antimicrob Agents Chemother       Date:  2006-06       Impact factor: 5.191

3.  Radioimmunotherapy is effective against high-inoculum Cryptococcus neoformans infection in mice and does not select for radiation-resistant cryptococcal cells.

Authors:  Ruth A Bryan; Zewei Jiang; Xianchun Huang; Alfred Morgenstern; Frank Bruchertseifer; Rani Sellers; Arturo Casadevall; Ekaterina Dadachova
Journal:  Antimicrob Agents Chemother       Date:  2009-01-12       Impact factor: 5.191

4.  Radioimmunotherapy of Cryptococcus neoformans spares bystander mammalian cells.

Authors:  Ruth A Bryan; Zewei Jiang; Alfred Morgenstern; Frank Bruchertseifer; Arturo Casadevall; Ekaterina Dadachova
Journal:  Future Microbiol       Date:  2013-09       Impact factor: 3.165

5.  Radioimmunotherapy is more effective than antifungal treatment in experimental cryptococcal infection.

Authors:  Ruth A Bryan; Zewei Jiang; Robertha C Howell; Alfred Morgenstern; Frank Bruchertseifer; Arturo Casadevall; Ekaterina Dadachova
Journal:  J Infect Dis       Date:  2010-08-15       Impact factor: 5.226

6.  Toward developing a universal treatment for fungal disease using radioimmunotherapy targeting common fungal antigens.

Authors:  R A Bryan; A J Guimaraes; S Hopcraft; Z Jiang; K Bonilla; A Morgenstern; F Bruchertseifer; M Del Poeta; A Torosantucci; A Cassone; J D Nosanchuk; A Casadevall; E Dadachova
Journal:  Mycopathologia       Date:  2011-11-03       Impact factor: 2.574

Review 7.  Radioimmunotherapy of infectious diseases.

Authors:  Ekaterina Dadachova; Arturo Casadevall
Journal:  Semin Nucl Med       Date:  2009-03       Impact factor: 4.446

8.  Feasibility of radioimmunotherapy of experimental pneumococcal infection.

Authors:  E Dadachova; T Burns; R A Bryan; C Apostolidis; M W Brechbiel; J D Nosanchuk; A Casadevall; L Pirofski
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

9.  Radiolabeled antibodies to Bacillus anthracis toxins are bactericidal and partially therapeutic in experimental murine anthrax.

Authors:  Johanna Rivera; Antonio S Nakouzi; Alfred Morgenstern; Frank Bruchertseifer; Ekaterina Dadachova; Arturo Casadevall
Journal:  Antimicrob Agents Chemother       Date:  2009-08-24       Impact factor: 5.191

Review 10.  Monoclonal antibody-based therapies for microbial diseases.

Authors:  Carolyn Saylor; Ekaterina Dadachova; Arturo Casadevall
Journal:  Vaccine       Date:  2009-12-30       Impact factor: 3.641
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.