| Literature DB >> 14980680 |
Dong Rack Choi1, Jung Han Shin, Jin Yang, Sue Hye Yoon, Yong Ho Jung.
Abstract
The design and syntheses of new fluoroquinolone antibacterial agents having pyrrolidine ring at C-7 position are described. The pyrrolidine ring is optically active and possesses methyloxime functional group. Two of them have excellent in vitro antibacterial activities and pharmacokinetic profiles.Entities:
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Year: 2004 PMID： 14980680 DOI： 10.1016/j.bmcl.2003.12.044
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823