Literature DB >> 14760739

Consensus design of repeat proteins.

Patrik Forrer1, H Kaspar Binz, Michael T Stumpp, Andreas Plückthun.   

Abstract

Consensus design is a valuable protein-engineering method that is based on statistical information derived from sequence alignments of homologous proteins. Recently, consensus design was adapted to repeat proteins. We discuss the potential of this novel repeat-based approach for the design of consensus repeat proteins and repeat protein libraries and summarize recent results from such experiments.

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Year:  2004        PMID: 14760739     DOI: 10.1002/cbic.200300762

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


  20 in total

1.  Folding of a designed simple ankyrin repeat protein.

Authors:  V Sathya Devi; H Kaspar Binz; Michael T Stumpp; Andreas Plückthun; Hans Rudolf Bosshard; Ilian Jelesarov
Journal:  Protein Sci       Date:  2004-11       Impact factor: 6.725

Review 2.  Genetic constraints on protein evolution.

Authors:  Manel Camps; Asael Herman; Ern Loh; Lawrence A Loeb
Journal:  Crit Rev Biochem Mol Biol       Date:  2007 Sep-Oct       Impact factor: 8.250

3.  The plastic landscape of repeat proteins.

Authors:  Diego U Ferreiro; Elizabeth A Komives
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-03       Impact factor: 11.205

Review 4.  Folding landscapes of ankyrin repeat proteins: experiments meet theory.

Authors:  Doug Barrick; Diego U Ferreiro; Elizabeth A Komives
Journal:  Curr Opin Struct Biol       Date:  2008-02       Impact factor: 6.809

5.  Mass discrimination in high-mass MALDI-MS.

Authors:  Simon Weidmann; Gediminas Mikutis; Konstantin Barylyuk; Renato Zenobi
Journal:  J Am Soc Mass Spectrom       Date:  2013-07-09       Impact factor: 3.109

6.  Stabilizing IkappaBalpha by "consensus" design.

Authors:  Diego U Ferreiro; Carla F Cervantes; Stephanie M E Truhlar; Samuel S Cho; Peter G Wolynes; Elizabeth A Komives
Journal:  J Mol Biol       Date:  2006-11-15       Impact factor: 5.469

7.  Consensus design of a NOD receptor leucine rich repeat domain with binding affinity for a muramyl dipeptide, a bacterial cell wall fragment.

Authors:  Rachael Parker; Ana Mercedes-Camacho; Tijana Z Grove
Journal:  Protein Sci       Date:  2014-04-17       Impact factor: 6.725

8.  Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins.

Authors:  Yi Guo; Chunhua Yuan; Feng Tian; Kun Huang; Christopher M Weghorst; Ming-Daw Tsai; Junan Li
Journal:  J Mol Biol       Date:  2010-04-14       Impact factor: 5.469

Review 9.  Nucleic acid recognition by tandem helical repeats.

Authors:  Emily H Rubinson; Brandt F Eichman
Journal:  Curr Opin Struct Biol       Date:  2011-12-09       Impact factor: 6.809

10.  Geometric constraints for porphyrin binding in helical protein binding sites.

Authors:  Christopher Negron; Christian Fufezan; Ronald L Koder
Journal:  Proteins       Date:  2009-02-01
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