| Literature DB >> 14742571 |
Gary R Matyas1, Arthur M Friedlander, Gregory M Glenn, Stephen Little, Jianmei Yu, Carl R Alving.
Abstract
Three immunizations of mice with recombinant protective antigen (rPA) by transcutaneous immunization (TCI) induced long-term neutralizing antibody titers that were superior to those obtained with aluminum-adsorbed rPA. In addition, rPA alone exhibited adjuvant activity for TCI. Forty-six weeks after completion of TCI, 100% protection was observed against lethal anthrax challenge.Entities:
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Year: 2004 PMID: 14742571 PMCID: PMC321625 DOI: 10.1128/IAI.72.2.1181-1183.2004
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441