Literature DB >> 14710378

The role of pharmacology in spinal cord protection during thoracic aortic reconstruction.

T Brett Reece1, John A Kern, Curtis G Tribble, David C Cassada.   

Abstract

Surgery of the thoracic aorta continues to have a significant risk of neurologic complication. Several strategies to minimize this risk are emerging. Pharmacologic protection from these complications continues to be researched, but at this point few medications are being used clinically. This article reviews the pathophysiology of ischemic spinal cord injury and summarizes the investigational pharmacology that may prevent these serious complications.

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Year:  2003        PMID： 14710378     DOI： 10.1053/s1043-0679(03)00088-1

Source DB:  PubMed          Journal:  Semin Thorac Cardiovasc Surg        ISSN： 1043-0679


  5 in total

Review 1.  Current strategies for spinal cord protection during thoracic and thoracoabdominal aortic aneurysm repair.

Authors:  Hideyuki Shimizu; Ryohei Yozu
Journal:  Gen Thorac Cardiovasc Surg       Date:  2011-03-30

2.  Evaluation of spinal cord protective threshold of serum memantine, an NMDA receptor antagonist, in a rabbit model of paraplegia.

Authors:  Nirmal Panthee; Minoru Ono; Takehito Yamamoto; Masako Ikemura; Tsuruhito Tanaka; Yoshifumi Itoda; Hiroshi Suzuki
Journal:  Indian J Thorac Cardiovasc Surg       Date:  2020-08-21

3.  Early adenosine receptor activation ameliorates spinal cord reperfusion injury.

Authors:  T Brett Reece; Curtis G Tribble; David O Okonkwo; Jonathon D Davis; Thomas S Maxey; Leo M Gazoni; Joel Linden; Irving L Kron; John A Kern
Journal:  J Cardiovasc Med (Hagerstown)       Date:  2008-04       Impact factor: 2.160

4.  Strategies to prevent and detect intraoperative spinal cord ischemia during complex aortic surgery: from drainages and biomarkers.

Authors:  Alexander Gombert; Florian Simon
Journal:  Neural Regen Res       Date:  2021-04       Impact factor: 5.135

5.  In Vivo Neuroprotective Effect of Histidine-Tryptophan-Ketoglutarate Solution in an Ischemia/Reperfusion Spinal Cord Injury Animal Model.

Authors:  Shin Kwang Kang; Min-Woong Kang; Youn Ju Rhee; Cuk-Seong Kim; Byeong Hwa Jeon; Sung Joon Han; Hyun Jin Cho; Myung Hoon Na; Jae-Hyeon Yu
Journal:  Korean J Thorac Cardiovasc Surg       Date:  2016-08-05
  5 in total

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